Practice Midterm-1

Practice Midterm-1 - NOTE: WRONG answers on multiple choice...

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NOTE : WRONG answers on multiple choice questions will result in the DEDUCTION of the points !!!!! 1) Explain the difference between a competitive antagonist and an inverse agonist! (10 pts) 2) Which of the following routes of drug administration is affected by the process known as “First Pass Elimination”? a) Topical b) Oral c) Rectal d) Subcutaneous e) Vaginal (5 pts each) 3) Which form of a drug is most readily absorbed across biological membranes: a) ionized b) protein bound c) unionized d) glucoronidated (5 pts each) 4) Provide an example for altered drug responses based on pharmacogenetic diversity! Explain! (15 pts) 5) When a loading dose is administered, the initial drug concentration is dependent on which of the following: a) elimination rate constant b) drug half-life c) volume of distribution d) clearance e) metabolism f) amount of drug administered (5 pts each) 6) Which drug, phentolamine or prazosin, is likely to be more effective in reducing high blood pressure? Justify your conclusion!
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Practice Midterm-1 - NOTE: WRONG answers on multiple choice...

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