Unformatted text preview: Antihypertensive medications. 3. Old drugs are sometimes marketed for new applications. Provide examples of two drugs that are marketed for their “side-effect.” Sildenfil () – antrihypertensive (vasodilator); also used to treat erectile dysfuntion Minoxidil (Rogaine) – antihypertensive (vasodilator); also promotes hair growth 4. Name the two methods used for new drug discovery. Drug screening – subject novel chemicals to a battery of tests designed to detect activity. Rational Design – specifically design compounds based on existing information 5. What is the underlying goal of the Orphan Drug Act? To give drug companies an incentive to develop drugs for diseases that affect less than 200,000 people in the US. 6. Briefly describe drug development starting with preclinical trials through Phase IV. Refer to lecture notes....
View Full Document
- Winter '09
- Pharmacology, Codeine, Codeine Resistance Codeine, Alcohol Dehydrogenase mutation, Acetalaldehyde Dehydrogenase mutation