2+Brain+development+2009+notes

2+Brain+development+2009+notes - Pathways of Brain...

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Pathways of Brain Development
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Are there ways to avoid some types of brain damage in infants?
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Fetal alcohol syndrome (FAS) Since 1991, the proportion of pregnant women drinking at least a glass of wine/beer/shot a day has quadrupled.
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FAS brains have increased cell death and altered cell migration
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• Mental retardation • Attention deficit disorders • Dyslexia • Decreases early testosterone surge in males Fetal alcohol syndrome
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95% will have mental health problems 60% will have disrupted schooling 60% will experience trouble with the law 82% will not be able to live independently Fetal Alcohol Syndrome (FAS)
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Glutamate is the brain’s dominant excitatory neurotransmitter and acts at several receptors, including the NMDA receptor. Blocking the receptor with MK-801 decreases neuronal activity. Excitatory and Inhibitory Neurotransmitters GABA is the dominant inhibitory neurotransmitter that acts on GABA receptors. Drugs such as the barbiturate phenobarbital increase the ability of these receptors to inhibit the neurons in response to GABA.
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cells commit suicide, leaving no inflammatory response that could injure other neurons. Cell Death
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This note was uploaded on 04/14/2010 for the course BIO SCI BIO N110 taught by Professor Leon,chance&parker during the Spring '09 term at UC Irvine.

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2+Brain+development+2009+notes - Pathways of Brain...

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