LeonKey - N110 Professor Leon SHORT-ANSWER QUESTIONS Name...

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N110: Professor Leon SHORT-ANSWER QUESTIONS Name two kinds of memories that H.M. has lost: A. ___ facts (explicit) ________ B. ___ events (explicit) ________ What are the three critical elements of any addictive drug? A. addiction B. tolerance C. compensatory response/withdrawal If you have a genetic female who has testis, what is the likely reason? Sxr (sex-reversed gene) (Sry gene on X instead of Y) Why doesn’t alpha-fetoprotein bind the estrogen in the brain cells of males? Alpha-fetoprotein is located outside brain cells, testosterone enters cell and is then turned into estrogen Name three drugs that cause cell death in the developing brain by decreasing NMDA activity. A. MK-801 B. Phencyclidine (PCP/Angel dust) C. anesthetics (nitrous oxide, ketamine) How might stress speed the progression of Alzheimer’s disease? stress produces cortisol, which can kill neurons via overactivation of NMDA receptors What is the only way to eliminate the learned compensatory response? _ extinction _________________
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What does the fact that people with Cushing’s Syndrome are prone to depression tell you about the basis for the emotional disorder? Cortisol involved in depression (Cushing’s patients have high cortisol levels) Name four things that people remember easily: information/info they _ process _________________ What happened to the short-term memories of “S”? How do glucocorticoids make neurons susceptible to ischemia? Name one drug and one endogenous agent that decreases Cl- flow via the GABAa receptor? What causes narcolepsy? Insufficient orexins (not enough orexin neuron activity b/c no/insufficient orexin NT) What are two major developmental cellular problems in FAS children. All consolidated to long-term (had synesthesia) Steal blood/glucose for large muscles, less available for the brain A. _ caffeine/DBI ________ B. _ allopregnalone _________
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Give three reasons why it is unlikely that a loss of serotonin is the cause of depression? A. __ patients don’t have low serotonin levels ______________________ B. _ 3-6 week lag in improvement even though medication affects serotonin quickly ___ C. _ depleting serotonin doesn’t produce depression _________________________ What two symptoms distinguish bulimia from anorexia? A. _ purging ______________ B. _ ~normal weight ________ If you are addicted and experience just the conditional stimuli associated with your drug, what will you experience? Addicted Viet Nam veterans returning to the U.S. failed to continue their drug use when they returned home. Were they still addicted? (Yes or No) No If you introduce large amounts of estrogen into a female fetus, will it masculinize or feminize her? masculinize Why might you want to test Memantine for stopping the cognitive loss attributable to stress?
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