chance-05.01 - NEUROBIOLOGY & BEHAVIOR BIO SCI N110 Spring...

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NEUROBIOLOGY & BEHAVIOR BIO SCI N110 Spring Quarter 2009 May 1, 2009
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More on the auditory system: 1.Tuning curves of inner hair cells and auditory nerves 2.The cochlear amplifier 3.Tonotopy in the cochlea and the auditory system 4.Theories of encoding sound “labeled-line theory” “volley theory” 5.Basic brainstem circuitry 6.Sound localization: medial superior olive uses interaural timing differences 7.Sound localization: LSO and MNTB use interaural intensity differences 8.Inferior colliculus 9.Auditory cortex
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tuning curves describe/measure what neurons are most sensitive to or what neurons encode responses of auditory nerves and inner hair cells are described by “tuning curves”
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example from book: threshold functions (commonly used when studying auditory system) characteristic frequency is the sound frequency that hair cells are most sensitive to
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Cochlear amplifier: 95% of projections from the cochlea to the brain come from inner hair cells outer hair cells are thought to actively increase basilar membrane movement by expanding/contracting in response to sound (essentially changing the flexibility of basilar membrane)
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evidence of “cochlear amplifier” 1) play a short noise (click) and your ear will produce sound suggests an active process “tinnitus” is a ringing in the ears - sometimes evidence of cochlear damage outer hair cells amplify basilar membrane vibration
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evidence of “cochlear amplifier” cont. 2) stimulation of olivocochlear bundle (efferent inputs to outer
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This note was uploaded on 04/14/2010 for the course BIO SCI BIO N110 taught by Professor Leon,chance&parker during the Spring '09 term at UC Irvine.

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chance-05.01 - NEUROBIOLOGY & BEHAVIOR BIO SCI N110 Spring...

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