Chapter 21 Testbank

Chapter 21 Testbank - Chapter 21 Lipid Biosynthesis...

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Chapter 21 Lipid Biosynthesis Multiple Choice Questions 1. Biosynthesis of fatty acids and eicosanoids Pages: 805-807 Difficulty: 2 Ans: E Which of the following is not required in the synthesis of fatty acids? A) Acetyl-CoA B) Biotin C) HCO 3 (CO 2 ) D) Malonyl-CoA E) NADH 2. Biosynthesis of fatty acids and eicosanoids Pages: 805-807 Difficulty: 2 Ans: B Which of the following is not true of the reaction producing malonyl-CoA during fatty acid synthesis? A) It is stimulated by citrate. B) It requires acyl carrier protein (ACP). C) It requires CO 2 (or bicarbonate). D) One mole of ATP is converted to ADP + P i for each malonyl-CoA synthesized. E) The cofactor is biotin. 3. Biosynthesis of fatty acids and eicosanoids Pages: 806-808 Difficulty: 3 Ans: D If malonyl-CoA is synthesized from 14 CO 2 and unlabeled acetyl-CoA, and the labeled malonate is then used for fatty acid synthesis, the final product (fatty acid) will have radioactive carbon in: A) every C. B) every even-numbered C-atom. C) every odd-numbered C-atom. D) no part of the molecule. E) only the omega-carbon atom (farthest carbon from C-1). 4. Biosynthesis of fatty acids and eicosanoids Page: 808 Difficulty: 2 Ans: E Which one of the following statements best applies to synthesis of fatty acids in E. coli extracts?: A) Acyl intermediates are thioesters of a low molecular weight protein called acyl carrier protein. B) CO 2 or HCO 3 is essential. C) Reducing equivalents are provided by NADPH D) The ultimate source of all the carbon atoms in the fatty acid product is acetyl-CoA. E) All of the above are true.
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Chapter 21 Lipid Biosynthesis 5. Biosynthesis of fatty acids and eicosanoids Pages: 811-812 Difficulty: 2 Ans: D In comparing fatty acid biosynthesis with β -oxidation of fatty acids, which of the following statements is incorrect ? A) A thioester derivative of crotonic acid ( trans -2-butenoic acid) is an intermediate in the synthetic path, but not in the degradative path. B) A thioester derivative of D- β -hydroxybutyrate is an intermediate in the synthetic path, but not in the degradative path. C) Fatty acid biosynthesis uses NADPH exclusively, whereas β -oxidation uses NAD + exclusively. D) Fatty acid degradation is catalyzed by cytosolic enzymes, fatty acid synthesis by mitochondrial enzymes. E) The condensation of two moles of acetyl-CoA in the presence of a crude extract is more rapid in bicarbonate buffer than in phosphate buffer at the same pH; the cleavage of acetoacetyl-CoA proceeds equally well in either buffer. 6. Biosynthesis of fatty acids and eicosanoids Page: 812 Difficulty: 2 Ans: E Which of the following is not true of the fatty acid synthase and the fatty acid β -oxidation systems? A)
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Chapter 21 Testbank - Chapter 21 Lipid Biosynthesis...

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