Exam 1 - Spr09 - EXIsp09 Multiple Choice Identify the...

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Multiple Choice Identify the choice that best completes the statement or answers the question. 1. A mild reducing agent will most likely affect which of the following amino acids in a protein? a. tryptophan d. cystine b. histidine e. lysine c. alanine 2. In what direction are the hydrogen bonds pointed in an alpha helical protein when compared to the central axis of the alpha helix? a. perpendicular d. 45 degrees b. 109 degrees e. parallel c. always the same as phi ( φ ) 3. Consider the following hexapeptide: trp-trp-val-met-trp-trp Treatment with which of the following will result in the maximum number of FREE amino acids? a. 6M HCl, heat, vacuum d. chymotrypsin b. cyanogen bromide e. Ellman’s reagent c. trypsin 4. A certain triprotic acid, H 3 A, has three distinct pK values. Which of the pK values will be most useful in preparing a buffer useful for experiments in the physiologically significant pH range? a. An average of all three pK values d. The highest pK b. Cannot answer without knowing the pK values first e. The middle pK c. The lowest pK 5. A weak acid is known to have a pK = 5.25. If the pH of a buffer prepared from this acid and its conjugate base is 4.25, what is the ratio of base to acid in this buffer?[note: you do not need a calculator to answer this question] a. 50 d. .1 b. .01 e. 10 c. 100 6. If the followiing hexapeptide were completely hydrolyzed to amino acids, separated by TLC and developed with ninhydrin, how many yellow spots would expect to observe? tryptophan-tyrosine-proline-proline-proline-methionine-hydroxyproline a. 3 d. 4 b. 6 e. 5 c. 2 7. Which of the following features of sodium palmitate will be closest to the surface of a micelle formed solely from assembly of sodium palmitate molecules? a. the omega carbon d. the alpha carbon b. methylene groups e. carboxylate anion c. methyl group 8. Which of the following is(are) generally NOT observed in proteins which exhibit a high degree of cooperativity in protein folding? a.
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This note was uploaded on 04/14/2010 for the course BHC 3023 taught by Professor Harmen during the Spring '10 term at University of South Florida - Tampa.

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Exam 1 - Spr09 - EXIsp09 Multiple Choice Identify the...

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