Exam 2 Fall 07

Exam 2 Fall 07 - Exam 2 - Fall 2007 Ch.5, 6, 7,8,10,11 1....

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Exam 2 - Fall 2007 Ch.5, 6, 7,8,10,11 1. Enzymes which act on monosaccharides to change the configuration around a specific carbon atom are called: a. transferases b. reductases c. ligases *d. epimerases e. rotisserases 2. A feature(s) of 2,3 bisphosphoglycerate that is essential for its ability to lower oxygen affinity for hemoglobin is: a. size *b. charge c. nucleophilicity d. hydrophobicity e. hydrophilicity 3. Individuals who have lactase deficiency are unable to hydrolyze: a. The alpha-1,4 linkage between galactose and galactose b. The alpha-1,4 linkage between galactose and glucose c. The alpha-1,6 linkage between galactose and glucose *d. The beta-1,4 linkage between galactose and glucose e. The beta-1,4 linkage between galactose and galactose 4. In an enzyme showing Michaelis-Menten kinetics, if the substrate level is 19 times the Km, what percentage of Vmax is the initial velocity vo? a. 99 b. 86 c. 90 d. 93 *e. 95 5. Given the following data on the rate of a reaction with and without inhibitor: Without inhibitor With inhibitor Km = 0.02 mM Km = 0.01 mM Vmax = 150 Vmax = 90 What type of inhibition is consistent with these results? a. competitive *b. uncompetitive c. mixed d. pure non-competitive e. covalent
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6. Which of the following pentapeptides is least likely to be buried completely inside a cell membrane? a. phe-glu-pro-leu-val b. pro-lys-val-ala-ala c. lys-glu-ser-glu-asp d. glu-glu-phe-leu-ile *e. phe-val-val-val-met 7. The reason why the Michaelisl-Menten curve cannot be used to extract the Km is: a. The Km value is out usually not in the range of the data used for the Michaelis-Menten plot. b. The Michaelis-Menten plot requires too many points for accurate determination of the
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Exam 2 Fall 07 - Exam 2 - Fall 2007 Ch.5, 6, 7,8,10,11 1....

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