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Population Genetics
Population:
group of interbreeding organisms similar in appearance and generally inhabiting the same geographic area.
Gene pool:
the sum total of all alleles distributed among the individuals of a population at a given point in time.
Genotypic frequencies:
the frequency of heterozygous and homozygous individuals in a population.
For example, the
frequency of heterozygotes in a population is determined by dividing the number of heterozygotes present, by the number of
total individuals in the population.
Allelic frequency:
the allelic frequency is the sum total of each allele in a population divided by the total number of alleles in
that population.
For example, if a population is composed of AA, Aa, and aa individuals, the frequency of A is equal to A
divided by the total number of all A’s and a’s.
The sum of these alleles is equal to 1.
HardyWeinberg equation represents genotypic frequencies:
p
2
+ 2pq + q
2
= 1, where p
2
= frequency of homozygous
dominants (AA); 2pq = heterozygotes (Aa); q
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 Spring '08
 Loeblich
 Genetics, Population Genetics

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