HDE 100C-4

HDE 100C-4 - HDE 100C Adult Development and Aging Topic...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
HDE 100C: Adult Development and Aging Topic: Biological Theories of Aging; Physiological Aspects of Aging Readings: Textbook Chapter 3 pp. 52-78 I. Types of Aging a. Primary aging: genetically encoded b. Secondary aging: related to disease, disuse, injury, and other environmental factors II. What is Aging? a. Normal biological aging = senescence b. Orderly changes in physiological and behavioral function across the adult years c. Gradual, inevitable, and universal changes III. Why Do We Age? a. Programmed longevity and aging i. Aging/longevity are outcomes of epigenesis ii. Genes processes exist to switch on and off iii. Epigenesis = genetically-controlled processes that regulate on vs. off state of particular genes b. Endocrine and hormonal changes i. Hormones regulate rate of aging ii. Biological clocks have effects on pace of aging via hormones c. Immunological changes i. Increased vulnerability to diseases due to immune system becoming less effective d. Metabolic effects i. Metabolism governs rate of biological processes which pace of aging ii. Faster metabolic rates faster aging shorter lifespan iii. Plausible mechanism for calorie restriction effects e. Cross-linking effects i. With aging proteins, DNA, and other molecules develop inappropriate links to one another ii. Accumulation of these cross links decreases mobility/elasticity of proteins and other molecules iii. Cross-linking reduces elimination of damaged products of protein synthesis (normally eaten up by proteases) loss of cell efficiency f. Telomere shortening i. Cell replacement from division telomeres getting shorter inability to replace damaged cells g. Free radical effects
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 4

HDE 100C-4 - HDE 100C Adult Development and Aging Topic...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online