1 Biology, 8e (Campbell) Chapter 18 Regulation of Gene Expression Multiple-Choice Questions 1) What does the operon model attempt to explain? A) the coordinated control of gene expression in bacteria B) bacterial resistance to antibiotics C) how genes move between homologous regions of DNA D) the mechanism of viral attachment to a host cell E) horizontal transmission of plant viruses Answer: A Topic: Concept 18.1 Skill: Knowledge/Comprehension 2) The role of a metabolite that controls a repressible operon is to A) bind to the promoter region and decrease the affinity of RNA polymerase for the promoter. B) bind to the operator region and block the attachment of RNA polymerase to the promoter. C) increase the production of inactive repressor proteins. D) bind to the repressor protein and inactivate it. E) bind to the repressor protein and activate it. Answer: E Topic: Concept 18.1 Skill: Knowledge/Comprehension 3) The tryptophan operon is a repressible operon that is 4) This protein is produced by a regulatory gene:
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2 Topic: Concept 18.1 Skill: Knowledge/Comprehension 5) A mutation in this section of DNA could influence the binding of RNA polymerase to the DNA: 6) A lack of this nonprotein molecule would result in the inability of the cell to "turn off" genes: A) operon B) inducer C) promoter D) repressor E) corepressor Answer: E Topic: Concept 18.1 Skill: Knowledge/Comprehension 7) When this is taken up by the cell, it binds to the repressor so that the repressor no longer binds to the operator: 8) A mutation that inactivates the regulatory gene of a repressible operon in an E. colicell would result in