Mic 101 Lecture 3 Metabolism

Mic 101 Lecture 3 Metabolism - Lecture 3. Basic...

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Unformatted text preview: Lecture 3. Basic biosynthetic metabolism Precursor to monomer Precursor Amount needed in mol to make 1 g of E. coli Monomers made from the precursor Glucose-6-phosphate 205 ADP-glucose, UDP-glucose (LPS), heptose (LPS) Fructose-6-phosphate 71 N-acetylglucosamine, N-acetylmuramic acid Ribose-5-phosphate 898 Amino acids, nucleotides Erythrose-4-phosphate 361 Amino acids Triose phosphate 129 Glycerol phosphate (lipids) 3-Phosphoglycerate 1,496 Amino acids, nucleotides, folic acid, heme Phosphoenolpyruvate 519 Amino acids, N-acetylmuramic acid Pyruvate 2,431 Amino acids Acetyl CoA 3,748 Fatty acids, amino acids 2-Oxoglutarate 1,079 Amino acids Oxalacetate 1,787 Amino acids, nucleotides Succinyl CoA not calculated Heme, amino acids (methionine, lysine) Summary of biosynthetic costs to make 1 gram of E. coli Polymer Monomer synthesis Polymerization Sum ~P Protein 7,287 21,970 29,257 RNA 6,540 256 6,796 DNA 1,090 136 1,226 Phospholipid 2,578 258 2,836 Peptidoglycan 248 138 386 Lipopolysaccharide...
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Mic 101 Lecture 3 Metabolism - Lecture 3. Basic...

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