Lect3powerpointSLIDES

Lect3powerpointSLIDES - Slides BIS 103 GLYCOLYSIS...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Slides BIS 103 4/6/10 GLYCOLYSIS Co-factors vitamin relationship “High energy” compounds NAD recycling Aerobic vs anaerobic glycolysis (fermentation) Alcohol metabolism in humans Thursday 4/8 Glucose -- ah, sugar sugar -- You are my favorite fuel From the blood-borne substrate pool. Glucose -- monosaccharide sugar -- You're sweeter than a woman's kiss 'Cause I need you for glycolysis. I just can't believe the way my muscles take you in. (For you, they'll open the door.) All it takes is a little bit of insulin (To upregulate GLUT4). Ah, glucose -- ah, sugar sugar -- You help me make ATP When my predators are chasing me. Ah, glucose -- you're an aldehyde sugar, And you're sweeter than a woman's kiss 'Cause I need you for glycolysis. I just can't believe the way my muscles break you down. (My glycogen is almost gone.) A few more seconds and I'll be rigor mortis-bound. (Acidosis done me wrong.) Your sweet is turning sour, baby. I'm losing all my power, baby. I'm gonna make your muscles ache. No, no, no! I'm swimming in lactate, baby. Yes, I'm swimming in lactate, baby. Now I'm drowning in lactate, baby. I'm gonna make your muscles ache. No, no, no! I'm swimming in lactate, baby. Ah, glucose -- ah, sugar sugar -- I used you up and you left me flat; Now I'll have to get my kicks from fat. Oh, glucose, glucose, sugar, sugar, The honeymoon is over now. GLUCOSE, GLUCOSE written by Jeff Barry and Andy Kim scientific lyrics by Greg Crowther http://www.science-groove.org/Now/Glucose.mp3 H CHO OH H HO OH H OH H CH 2 OH H CHO OH H HO OH H OH H CH 2 OPO 3 2- GLC-6-P GLC ATP ADP CH 2 OH O H HO OH H OH H CH 2 OPO 3 2- ATP ADP CH 2 OPO 3 2- O H HO OH H OH H CH 2 OPO 3 2- CH 2 OPO 3 2- O CH 2 OH H HC OH CH 2 OPO 3 2- + HPO 4 2- NAD + NADH H C OH CH 2 OPO 3 2- O OPO 3 2- ATP ADP H C OH CH 2 OPO 3 2- O- O H C OPO 3 2- CH 2 OH O- O C OPO 3 2- CH 2 O- O C O CH 3 O- O ATP ADP F-6-P DHAP G-3-P 1,3 bisPGA 3-PGA 2-PGA PEP PYR H 2 O 1 2 3 4 5 6 7 8 9 10 on a per glucose basis, from here multiple all by 2 H O OH H OH H OH CH 2 OH OH H O OH H OH H OH CH 2 OPO 3 2- OH ATP ADP 1 2 O 3 POH 2 C OH CH 2 OH H OH H H OH O O 3 POH 2 C OH CH 2 OPO 3 2- H OH H H OH O ATP ADP 3 Fischer projection-open chain Ring form O F-1,6-bisP + H + 1 2 3 4 5 6 1 2 3 4 5 6 1,6 2,5 3,4 Haworth projection [ 11 ] Aerobic Glycolysis HB pg 11 Glycolysis, step 1 Not physiologically reversible- note arrow H CHO OH H HO OH H OH H CH 2 OH H CHO OH H HO OH H OH H CH 2 OPO 3 2- GLC-6-P GLC ATP ADP 1 Kinase Hexokinase In mammalian liver- glucokinase HB pg 11 Glycolysis, step 2...
View Full Document

This note was uploaded on 04/16/2010 for the course BIS 103 taught by Professor Abel during the Spring '08 term at UC Davis.

Page1 / 39

Lect3powerpointSLIDES - Slides BIS 103 GLYCOLYSIS...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online