Lecture6powerpointslides

Lecture6powerpointslides - Slides Thursday April 15, 2010...

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Unformatted text preview: Slides Thursday April 15, 2010 • Taxes due! • Misc • TCA cycle – Reactions, uses REVIEW SESSIONS? Study Guide, Master Lists ALLOZYMES: Variant enzymes forms coded by different alleles at the same locus. Example from class: ALDH2 Glu and Lys enzymes are allozymes. ISOZYMES: Enzymes that perform the same function, but which are coded by genes at different loci. Example from class: ALDH1 and ALDH2 are isozymes. C O H 3 C SCoA CH 2 COO- CH 2 COO- HO COO- CH 2 COO- C CHCOO- COO- CH 2 COO- C H COO- COO- OH CH 2 COO- C H H COO- O CH 2 COO- C H H ScoA O + CO 2 COO- CH 2 CH 2 COO- GDP + Pi GTP + CoASH COO- C C- OOC H H C COO- C H HO H H COO- + H + ISOCITRATE !-KETO- GLUTARATE SUCCINYL CoA C COO- H 2 C COO- O Acetyl CoA TCA CYCLE CITRATE cis-aconitate enzyme-bound OXALOACETATE FUMARATE SUCCINATE MALATE 1 2 3 4 5 6 7 8 CoASH + H + 2 NAD NADH CO 2 NAD NADH CoASH FADH 2 FAD H 2 O NAD NADH H 2 O H 2 O H 2 O H 1 H 2 C CH 2 COO- HO COO- C SCoA O NZ bound intermediate citryl CoA C o m m o n S y s t e m a t i c . 1. citrate synthase citrate OAA-lyase (acetyl CoA forming) 2. aconitase citrate hydro-lyase 3. isocitrate dehydrogenase isocitrate:NAD+ oxidoreductase(decarboxylating) 4. !-ketoglutarate dehydrogenase complex !-ketoglutarate dehydrogenase system 5. succinyl CoA synthetase succinate:CoA ligase (GDP forming)5....
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This note was uploaded on 04/16/2010 for the course BIS 103 taught by Professor Abel during the Spring '08 term at UC Davis.

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Lecture6powerpointslides - Slides Thursday April 15, 2010...

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