Glycolysis Handout Payoff

Glycolysis Handout - Step 7 A phosphate group is removed from each 1,3-bisphosphoglycerate to make two ATP and 3-phosphoglycerate This reaction is

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www.thinkwell.com [email protected] Copyright © 2000, Thinkwell Corp., All Rights Reserved. 1199bio92 Glycolysis: The Energy Payoff ª Review : The energy investment phase of glycolysis involves the investment of two ATP molecules and results in the formation of two molecules of glyceraldehyde phosphate. ª The energy payoff phase of glycolysis consists of five additional steps and results in the formation of four ATP , two NADH + H + , and two pyruvate molecules. ª Substrate level phosphorylation is the process by which ATP is produced from the transfer of a phosphate group from a substrate molecule in a metabolic pathway. Step 6 : Glyceraldehyde phosphate is oxidized (NAD + is reduced) and phosphorylated by the enzyme triose phosphate dehydrogenase to produce 1,3- bisphosphoglycerate. Two molecules of NADH + H + are produced. This is an example of a coupled reaction . The highly exergonic redox reaction fueled the endergonic formation of the phosphate bond.
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Unformatted text preview: Step 7 : A phosphate group is removed from each 1,3-bisphosphoglycerate to make two ATP and 3-phosphoglycerate. This reaction is mediated by the enzyme phospho-glycerokinase. This reaction is an example of substrate level phosphorylation . A phosphate group was removed from a substrate molecule and added to ADP to make ATP. Step 8 : The remaining phosphate group is transferred to the middle carbon by the enzyme phosphoglyceromutase. This reaction will energize the molecule and make it less stable. 2-phosphoglycerate results. www.thinkwell.com [email protected] Copyright © 2000, Thinkwell Corp., All Rights Reserved. 1199bio92 Step 9 : A water molecule is removed and a double bond is added to both 2-phosphoglycerate molecules to produce two phosphoenolpyruvate (also known as PEP) molecules. Step 10 : Both PEP molecules are dephosphorylated by pyruvate kinase to produce two pyruvates and two ATP....
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This note was uploaded on 04/16/2010 for the course BIS 103 taught by Professor Abel during the Spring '08 term at UC Davis.

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Glycolysis Handout - Step 7 A phosphate group is removed from each 1,3-bisphosphoglycerate to make two ATP and 3-phosphoglycerate This reaction is

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