NSF Tbx5 and heart evolution

NSF Tbx5 and heart evolution - nsf.gov - National Science...

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NSF Web Site News News News From the Field For the News Media Special Reports Research Overviews NSF-Wide Investments NSF Current Newsletter Multimedia Gallery News Archive News by Research Area Biology Computing Education Engineering Mathematics Nanoscience Physics Press Release 09-164 Secrets of the Four Chambers Revealed by Reptile Hearts The molecular blueprint for evolution from cold-blooded to warm-blooded has been found Embryo hearts show evolution of the heart from 3-chambered in frogs to 4-chambered in mammals. Credit and Larger Version September 1, 2009 Watch an interview with developmental cardiologist Benoit Bruneau. The first genetic link in the evolution of the heart from three- chambered to four-chambered has been found, illuminating part of the puzzle of how birds and mammals became warm-blooded. Frogs have a three-chambered heart. It consists of two atria and one ventricle. As the right side of a frog's heart receives deoxygenated blood from the body, and the left side receives freshly oxygenated blood from the lungs, the two streams of blood mix together in the ventricle, sending out a concoction that is not fully oxygenated to the rest of the frog's body. Turtles are a curious transition--they still have three chambers, but a wall, or septum is beginning to form in the single ventricle. This change affords the turtle's body blood that is slightly richer
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This note was uploaded on 04/17/2010 for the course BIO 201 taught by Professor True during the Spring '08 term at SUNY Stony Brook.

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NSF Tbx5 and heart evolution - nsf.gov - National Science...

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