1984 1996 Essays - Andre Mallqui 1984 Hershey and Chase...

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Andre Mallqui 1984 Hershey and Chase dealt with bacteriophage replication answering the question of which viral component (either protein or DNA) was responsible for the reprogramming of the host cells to produce viruses. For their experiment they used E. Coli. They first labeled the phage cultures in 32P and 35S. They would attempt the recovery of labeled viruses through the reinjection of bacteria in different temperatures, on being cold the other hot. The results concluded that the 32P culture had a endogenous recovery and 35S had a exogenous recovery. In culture 35S association was given recognition to proteins, while in culture 32P it was DNA. It essentially concluded that nucleic acids, rather than proteins, are the hereditary material for viruses. Griffith and Avery dealt with bacterial transformation and the issues and question over the identity of the substance involved in transformation. Griffith had two strains of a bacterium, one that was pathogenic the other variant that was harmless.
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