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Lec 16 - Q Strawberry plants send out long branches(runners...

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Q: Strawberry plants send out long branches (runners) with a small plant at the end of each runner. If you cut the runners you can have many plants of the same genotype. Suppose you collect 20 plants of genotype #1 and grow 10 in the sun, 10 in the shade. On average, the plants of genotype #1 have bigger leaves when grown in the shade than when grown in the sun. If this were interesting to you, what would you be studying? a) genetic effects b) epistasis c) environmental effects d) pleiotropy e) co-dominance
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Which of the following are likely to be polygenic traits? tail length in mice leg length in grasshoppers skin color in humans height in humans fur color in rabbits feather color in blue and green budgies
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BIS2B Fall 2009 (Keen) Lecture 16 . Introduction to Population Genetics !" $%&’()* +’*,-,. +))&-,. / *)+-,0)* ’, +1&2&-’,3 45’*& 0)4%*-6&-’, ’7 &5) +’0)*, 48,&5)4-43 -,&*’01%&-’, &’ 6’6192&-’, .),)&-%4 :&10),&4 45’190 () 2(9) &’; ’1&9-,) &5) +’0)*, 48,&5)4-4 <.),)&-%4 = ,2&1*29 4)9)%&-’,> %29%192&) 299)9) 2,0 .),’&86) 7*)?1),%-)4 )@692-, &5) .’29 ’7 6’6192&-’, .),)&-%4 .-A) 2, )@2+69) ’7 2, )?1-9-(*-1+ )@692-, B58 C2*08DE)-,()*. )?1-9-(*-1+ *)6*)4),&4 2 ,199 586’&5)4-4 ’1&9-,) &5) F 2441+6&-’,4 ’7 C2*08DE)-,()*. )?1-9-(*-1+
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BIS2B Fall 2009 (Keen) Lecture 16 . Introduction to Population Genetics !" $%&’()* +’*,-,. +))&-,. / *)+-,0)* ’, +1&2&-’,3 45’*& 0)4%*-6&-’, ’7 &5) +’0)*, 48,&5)4-43 -,&*’01%&-’, &’ 6’6192&-’, .),)&-%4 :&10),&4 45’190 () 2(9) &’; ’1&9-,) &5) +’0)*, 48,&5)4-4 <.),)&-%4 = ,2&1*29 4)9)%&-’,> %29%192&) 299)9) 2,0 .),’&86) 7*)?1),%-)4 )@692-, &5) .’29 ’7 6’6192&-’, .),)&-%4 .-A) 2, )@2+69) ’7 2, )?1-9-(*-1+ )@692-, B58 C2*08DE)-,()*. )?1-9-(*-1+ *)6*)4),&4 2 ,199 586’&5)4-4 ’1&9-,) &5) F 2441+6&-’,4 ’7 C2*08DE)-,()*. )?1-9-(*-1+
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!"#$ !"#" !""% !"%& !"%’ !%(( !%(& !%($ !%(% !%!( !%!$ !"#$"% ’()’)*"* "+,*-"#." )/ 0121345627 862549:1; 3<(=,# ’()’)*"* -><- ?"@@A%"* -(<#*@,- -(<,-* 0A?) $" B(,"* $"C"%)’* .)#."’- )/ ’<#?"#"* D*’".,<% ’<(-,.%"* /)( "C"(E >"("$,-<(E .><(<.-"(F G",**@<## ’()’)*"* -><- >"("$,-<(E ’<(-,.%"* ("*,$" )# .>()@)*)@"* $"B(,"*H 9)(("#*H I C)# ;"E*"##"?? 2134;9JB12 !1K31:L; GJ2M 1N ON G,%*)# $"*.(,P"* P"><C,)( )/ .>()@)*)@"* $A(,#? "@P(E) $"C"%)’@"#- G,%>"%@ G<%$"E"( ,$"#-,/,"* 902J!J;J!1; G,%*)# I *-A$"#-* .)#/,(@ !14J;4; 4; 213Q954JK 34B4;4JK RJ2 S6!151; G,%*)# I ;A--)# ,$"#-,/E *"+ .>()@)*)@"* T)><##*"# $,*-,#?A,*>"* P"-=""# S1KJ5781 B; 801KJ5781 !)(?<# <(?A"* <?<,#*- ()%" )/ .>()@)*)@"* ,# ,#>"(,-<#." !)(?<# "<-* .()= I <[email protected],-* -><- 902J!J;J!1; O162 862549Q:651 QK45; JR 4K012456K91U Development of a theory of inheritance
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KQ9:1J5431 ;QO;545Q54JK; SILENT (synonymous) (no effect on AA sequence) NEUTRAL (non-synonymous) (substituted AA functionally equivalent) MISSENSE (non-synonymous) (AA change) NONSENSE (non-synonymous) (unexpected STOP codon) Reminder on mutations: Point Mutations )*+, )*+,- ./01 ./01 )*+, )*+,- ./01 ./01 )*+, )*+,- ./01 )*+, )*+,- ./01 ./01 2345678 9:;;32;3 9:;;32;3 ;:8325 ;:8325 2<2;32;3 2<2;32;3
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6#)->"( 8),#- !A-<-,)# 6#)->"( 8),#- !A-<-,)# Frameshift mutations =>[email protected]?*A *[email protected]*CBD,1+1.*CBE
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