# Lec 17 - BIS2B Fall 2009(Keen Lecture 17 More on Population...

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BIS2B Fall 2009 (Keen) Lecture 17 . More on Population Genetics !" \$%&’()* +,&)*-’’- %./00 12’./&2’-0 ’, &3) /00456&2’-0 ’, 78 )942.2(*245 :&4;)-&0 03’4.; () /(.) &’< 6*);2%& &3) ),,)%&0 ’, =2’./&2’-0 ’, &3) > %’-;2&2’-0 ,’* 78 ’- &3) ’(0)*=); ?)-’&@62% ,*)94)-%2)0A 6*);2%& &3) ),,)%&0 ’, -/&4*/. 0).)%&2’- ’- ;20%*)&) /-; 94/-&2&/&2=) &*/2& ;20&*2(4&2’-0 2- ,4&4*) ?)-)*/&2’-0B C2&3 06)%2/. *),)*)-%) &’ &3) 5)/- /-; =/*2/-%) ’, 94/-&2&/&2=) &*/2& ;20&*2(4&2’-0A

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Fitness is measured on individuals , but we see evolution as gene frequency change within populations across generations. Individuals do not evolve, populations evolve.
The observed frequencies from the data set in the last lecture were: f (YY) = 0.48 , f (Yy) = 0.24, f (yy) = 0.28 Make a table: f (YY) f (Yy) f (yy) Expected Observed Departures excess YY heterozygote deficiency excess yy .48 . 24 . 28 .36 . 48 .16

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Which violations could cause this? In diploid organisms, gene/allelic frequencies & In diploid organisms, gene/allelic frequencies & genotypic ratios in large genotypic ratios in large biparental populations populations reach an equilibrium in 1 generation, and remain reach an equilibrium in 1 generation, and remain constant thereafter, when constant thereafter, when … 1. large population size (no genetic drift) 2. no migration (gene flow from other populations 3. no mutations 4. random mating 5. no advantages to alleles (natural selection) SO: what about small population size and genetic drift, gene flow, mutations, non- random mating and natural selection? What effect will they have?
Which violations could cause this?

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