Lecture 14 - BioE10 Lecture 14 Professor Irina Conboy...

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BioE10: Lecture 14 Professor Irina Conboy BioE10: Lecture 14 Tissue engineering/Regenerative Medicine Immune System and tissue engineering
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ECM is one of the main components used in tissue engineering Antibodies, chemokines and cells of the immune system are useful b ildi bl k i d d bi t i l 1. Collagen, fibrin, laminin= natural ECM 2. Alginate and chitosan= glycansextracted from brown algae and the exoskeleton of building blocks in advanced biomaterials 2. Alginate and chitosan glycansextracted from brown algae and the exoskeleton of shellfish, respectively 3.Poly(L lactic acid) (PLLA), poly(glycolic acid) (PGA), poly(ethylene glycol) (PEG), polycaprolactones, polyorthoesters, polyanhydridesand polycarbonates = synthetic l polymers. 1). Inhibiting cancer growth with the help of designer ECM (comparison with currently used anti cancer therapies). 2). Enhancing Vascularizationwith the help of designer ECM 3). Rejuvenating and Enhancing Tissue Regeneration with the help of designer ECM
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Trends in biotechnology, vol26, No7 Cancer-specific protein; Cancer specific protein; Q: how to identify the antigen for anti-cancer vaccination?
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Q: What is an example of a tolerance-promoting antigen?
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