Question_bank_2010 - HOLLINGSWORTH QUESTION BANK 2010 All...

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1 HOLLINGSWORTH QUESTION BANK 2010 All questions are from midterms or finals generated by me from 1996 to 2009. Please note that many questions integrate ideas from more than one lecture and therefore may be applicable to more than one category. However, to keep the size of the bank manageable, each question is only listed once. (Answer key at the back). Table of contents: A. Vocabulary 1 B. Mendelian Genetics 2 C. Exceptions to Mendelian Genetics 6 D. Mitosis and Meiosis 13 E. Sex linkage and sex-limited traits 17 F. Pedigree Analysis 20 G. χ 2 Problems 23 H . Linkage and Gene Mapping: Inter-genic recombination 26 I. Chromosome Aberrations 37 J. DNA Structure 42 K. DNA replication, mismatch repair and recombination 45 L. Mutation 50 M. Linkage and Gene Mapping: Intra-genic recombination 55 N. Gene Function 61 O. Prokaryotic Genetics 67 P. Extrachromosomal Inheritance 71 Answer Key 72 A. VOCABULARY A1. For each of the terms in the left column, choose the best matching phrase in the right column and put the number in the space next to the letter. _____ A . alleles 1. less than 100% of the individuals possessing a particular genotype display it in their phenotype _____ B. independent assortment 2. one gene affecting more than one phenotype _____ C. heterozygote 3 . the alleles of one gene mask the effects of alleles of another gene _____ D. locus 4. an individual with two different alleles of a gene _____ E. epistasis 5. observable characteristic _____ F. pleiotropy 6. alternate forms of a gene _____ G. reduced penetrance 7. alleles of one gene separate into gametes randomly with respect to alleles of other genes _____ H. tetratype 8. the relative chromosomal location of a gene _____ I. interference 9. one crossover along a chromosome makes a second nearby crossover less likely _____ J. phenotype 10. an ascus containing spores of four different genotypes A2. Fill in the blank. a. During DNA synthesis, the _______________________strand is synthesized discontinuously. b. An allele that affects more than phenotype is __________________________. c. __________________________ is when the genotype of one locus masks the phenotype of a second locus.
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2 d. A base pair substitution that changes a purine on one strand to a pyrimidine is called a _______________________________. e. ________________________ describes the proportion of individuals of a given genotype that displays the phenotype associated with that genotype. A3. Give the word that fits each definition. 1. ____________________ The degree or severity of a phenotype. 2.____________________ Chromosomes with highly similar, but not necessarily identical, DNA sequences. 3_____________________ Type of inversion that contains the centromere. 4. ____________________ One or more sets of chromosomes within an organism is incomplete. 5. ____________________ Type of tetrad formed by a four strand double crossover between two genes in yeast. B. MENDELIAN GENETICS: B1. A dominant allele is one that: A. expresses a phenotype only when homozygous. B. masks the expression of neighboring gene loci. C. expresses a phenotype only when heterozygous.
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Question_bank_2010 - HOLLINGSWORTH QUESTION BANK 2010 All...

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