Lecture-7-Membrane-S_37964

Lecture-7-Membrane-S_37964 - MembraneStructure&Function

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ell interior –sepa ra te the cell from its surroundings lasma membrane) • Biological membranes are molecular boundaries that: Cell interior Plasma membrane (plasma membrane) – compartmentalize biological functions (organelles) External environment – function to control the exchange of materials into/out of the cell or rganelle ( lective permeability organelle ( selective permeability ) re constituents of membranes Head group hosphate core constituents of membranes. –A l so present: carbohydrates, other lipid types Phosphate Glycerol –Memb rane formation is due to the Fatty acids
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Membrane Structure according to the fluid mosaic model: roteins are embedded in or attached to a phospholipid bilayer – Proteins are embedded in, or attached to, a phospholipid bilayer Phospholipid bilayer ddition of proteins to bilayer: •P ro te in s provide the functionality to membranes; Addition of proteins to bilayer: forms a “fluid
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Membranes are Dynamic •W e a k, hydrophobic interactions hold together membrane mponents components proteins exhibit lateral movement in a membrane. •M e m b r a n e fluidity is critical to function; changes in fluidity alter •M e m b r a n e fluidity is determined permeability. by the degree of saturation of phospholipid fatty acid tails. – Temperature response: cooler Æ membrane more viscous warm Æ membrane more fluid –Cho le s
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Animal Cell Plasma Membrane
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Membrane Proteins Integral proteins : penetrate the hydrophobic core of the membrane transmembrane proteins : spans the membrane and protrudes on either or both p sides of membrane. –In teg ra l proteins are amphipathic –Some possess hydrophilic annel passing through channel passing through the center eripheral membrane proteins: Periphera l protein ytoplasmic side Peripheral membrane proteins: loosely attached to membrane surface; often to exposed portions of integral proteins Cytoplasmic side •S o m
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Membrane Protein Functions Membrane carbohydrates function in cellular recognition : – formation of tissues, organs
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Lecture-7-Membrane-S_37964 - MembraneStructure&Function

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