Test 3 Mammalian - ' 5 Put your name on the front and on...

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Unformatted text preview: ' 5 Put your name on the front and on the back Name___ W Section_ IN THE PROBLEMS, SHOW ALL YOUR WORK AND CIRCLE YOUR ANSWERS!!! ,1. Define renal clearance 4 ’ - 1. .A y} i ‘4 Mia iyfpfllimififi P/asma Volume 5 amiarflwjr M< 0"” a + mp ‘7‘“ t 6 u bslmmé excé-Q 65 ‘m gut a." gm}?! n+5? 2. Calculate the renal clearance of substance X given the following information Hematocrit 45 Plasma concentration of X 5 mg/200 ml GFR 100 ml/min Concentration of X in urine 75 mg/5 ml Renal fraction 25% Urine volume 150 nil/hr ) Ami-ea" obi? 60M . ~ Vi — mama. - l - l \ — A . K. ‘ if —, 37,3“éizm Lflaswii M Qbiflafflx .1 '— .,a 2 , 0 Z S Ma, ' Mm (Wi- ZDOAL . J ML 025 3. Calculate the GFR given the following Tubular load of X 400 mg/nnn Renal blood volume 1000 ml/min Filtration fraction 20 % TmaX ofx 600 mg/min Plasma concentration of X 3 mg/ml" Urine volume 6 ml/Inin ‘ Cardiacoutput 6000 ml/min / (D r ’ i « M“ I m I, i-fg 2: 24453144 ( (pr/Z: Kw M‘F LAM Q P - ’ AL bf. TL 1 5-!» 9": r‘ ’ "x ~ I” ' "5 6'3 ’ I z Lyn _. MG : l: '/35,_5§a:5: ‘w-(pm’y “i? Mi» ' ' / : I Mi." 7: a r fi 3 A M L w 7 xi we m. ' 5 ~ T \ I 4 ' 3Y7; I ‘ #:3th L M Z em} / ‘ "A\\A: {Dcfi C. (Qa‘rfinigf 1 4. Calculate Bowman’s capsule pressure given the. following: GFR Atmospheric pressure Glomerular blood pressure Mean arterial blood pressure Plasma Protein Osmotic Pressure Interstitial fluid pressure Interpleural pressure PAH clearance Filtration pressure Urine volume Creatinine clearance Filtration fiaction Tmax of X Hematocrit Renal fraction - _. Ejection fraction KEN r CQOM 2F?) _ F (C cfaal'ieFK 616R * K?“ CF ’ZOJ aver/C YOU '1 {JFK} (ung V T— ; KPV .15 KM = {dim {HM} <too '* ($869 .2: to 6—5”: .200 ml/min 760 mmHg 80 mmHg 95 mmI-Ig 5. Calculate the cardiac output given the following: 180 ml/hr 200 25% 200 mg/min 4O 20% . 75% a G '- 6. Calculate the T max of x given the following infOrmation Renal blood volume 4000 nil/min p50 45 ' Hematocrit 50 Renal fraction 1 20% Filtration fraction . 10% Plasma concentration of x 3 mg/ml Urine volume 45 ml/ 15 min Filtration pressure 20 mmHg Urine concentration of X 60 mg/Sml r mez/a z/CPT Timur/E xipks} Isrv=135°LHU3 TM = n r ml; era. om = F1 W “F5 ' I ~- :1“ {C art 4 mm = HCAKDK) (v ,3} "L 1 (pp/z ‘11 [pins] A flwr’iV-C ' L 52M RPVt'ZJDOO : ZODK 3 - {if K ,jaflxgm (91:2: swim 5”” F“ 7 : (9 oo 1 1000 (A3 L (pm :. 2,00 TM 1 TL ’ a “’3‘ “L‘ : (D o ' 7. Calculate the T—10 ad of growth hormone given tation PAH clearance 2000 Filtration fraction 10% _ Hematocrit 50 Plasma concentration of growth hormone 2 mg/ml Renal fraction , '1 25% W“ ’.lal>5.r' . Muller I\«V‘ "\"\)\\\\3'.\/ 8. Calculate the renal plasma threshold given the following Concentration of x in urine 30 mg/ml Renal fraction 20 % Cardiac output 6000 ml/min Hematocrit I 40 Urine Volume 60 ml/20 min Plasma concentration of x 4 mg/ml Filtration fraction 30% v p50 45 * s KPT; E (W: (Comm/war} TL '4‘"? “ 4",“ ‘ GFK , r 2250 x Ll “- (900001.300) ' = 5M ‘ {a 2.110 v , , . ;‘_C I 1'l Git/Z: KP” ‘FF Axe-’UDQW: V - , Orr 2w 1‘ 210 /M Z 7(. 'fiml‘f‘“ lo” "M 1 fa!" ' 010 a 771—/ FOR ALL REMAINING QUESTIONS PUT YOUR ANSWERS ON THE SCAN SHEET. ONLY THESE ANSWERS WILL BE GRADED. ASSUME NORMAL CONDITIONS UNLESS TOLD OTHERWISE. I ' f‘ ,r’r 1. The following decrease urine volume - \ / A. Stimulating the Osmoreceptors D. All of these X B. AN? Two ofthese / C. Aldosterone 2. The following would describe the sequence of structures that a single molecule of ,glgggse‘would encounter in the kidney under normal conditions: Only the sequence is importaht; interVCDing structures may be omitted. - )(A Interlobular artery, arcuate artery, glomerulus, peritubular capillary netWork ' “ B. Glomerulus, Bowman’s capsule, Ascending Loop of Henle, renal vein «(Q Renal artery, afferent arteriole, PCT, peritubular capillary network XD. Efferent arteriole, glomerulus, peritubular capillary network, renal vein. B. More than one correct answer ' 3. Juxtaglomerular nephrons A. Have a progressively hypertonic medulla \/ B. Vasa recta J C. Macula densa . All ofthese Two ofthese i 4. Podocytes )(A. Form fenestra X B. Are part of the glomerulus \/@ Are under the influence of ANP D. All of these E. Two of these 5. Secretion 1M} (ilk '- 33 4.7: ./ . Occurs atthe glomerulus WflL‘j/ofl MINI": 0"? tat/95W“) @ Increases the clearance of a substance [NW ‘ ‘. Of sodium is affected by aldosterone (13. Two of these B. All of these 6. AN? J A. Increases the clearance of sodium ~ xB. Inhibits ADH secretion »/ C. Inhibits rennin secretion (13. All of these E. Two of these 7. The macula densa , ‘) X A. Is found in the collecting duct , J69. Causes the afferent arteriole to dilate when it detects too little sodium in the filtrate x C. Produces renin D. Two of these ' E. None Ofthese. ,1”: W‘ (M, «o “LI,” \ _ 8. Assume a renal plasma threshold of glucose of 3mg/ml and a plasma concentration of L >TM glucose of 4 rug/ml. Which of the following is/are true? , ' V / A. The concentration of glucose'inthe afferent and'efferent arterioles will be ' equal ' . p ' ‘ \/ B. The amount of glucose in the renal artery will be greater than that in the renal vein. _, , . \/ C. The amount of glucose in Bowman’s capsule will be greaterthan the amount of glucose in the ascending Loop of Henle @ All of these E. Two ofthese. I ? TA 9. Assume the same conditions and choices as #8 except assume that the renal plasma x threshold 18 equal to 5 mg/ml. x/ A - )( b J C ® 10. Calcium / A. Is freely filtered x B. Actively secreted under the influence of parathyroid hormone J C. Is in equal concentration in the efferent and afferent arterioles @ Two of these B. All of these 11. The ascending Loop of Henle / A. Actively secretes sodium ' KB. Is impermeable to water unless influenced by ADH 9 Has a thick portion and a thin portion '. All of these 69. Two of these 12. Aloop diuretic VA. Furosimide ‘ v’l3. Lasix ' C. Dyazide D. All of these E. Two of these 13. People Who have acidosis l/ A. May become comatose in the uncompensated state if B. May excrete an acidic urine in the compensated state /< C. Stop filtering bicarbonate D. All of these (9. Two of these 14. People with respiratory acidosis K A. Increase their ventilation rate to get rid of the C02 / B. May have more ammoniUm ion in their urine, ~ JC. May have emphysema D. All of these (9 . Two ofthese 15‘ People with untreated diabetes mellitus « f A. Have a glycosuria . ‘L B. May increase excrete more @32PO4 than a normal person / C. May have an acidic urine ' D. All ofthese ’@ Two of these 16. The following inhibit activity of the nucleus tractus solitarius /A. Pneumotaxic center KB. Vasomotor center )4 C. Nucleus retro-ambigualis D. All of these E. Two of these 17. The following stimulate respiration \/ A. Electrical activity in the spinal cord / B. Hydrogen ions directly stimulating the medullary chemoreceptors 1C. Herring Breuer reflex D. All of these @ Two of these 18. The nasopharynx A. Communicates directly with the Eustachian tubes \) B. Communicates directly with the oropharynx C. Contains the adenoids ' D. All of these E. None of these 19. The larynx XA. Contains a pair of thyroid cartilages— XB. Contains the carina - ' \/© Contains the vocal cords D. All of these E. Two of these 20. In a systemic capillary . p / A. Hemoglobin gives up oxygen because the partial pressure of oXygen falls K B. The Haldane effect occurs , )6 C. The hemoglobin dis association curve shifts to the left D. All of these E. Two ofthese 21. At high altitude * \/ A. Humans produce more erythropoietin ‘ J B. Humans oxyhemoglobin disassociation curves shift to the right \/ . The partial pressure of oxygen declines ' . All of these E. Two of these ‘ 22. Int red blood cell most of the carbon dioxide is carried in this form Carbaminohemoglobin Bicarbonate C. Carboxyhemoglobin D. C02 in solution B. None ofthese 23}. The site of erythropoietin synthesis in an adult A. Liver D. Spleen ' B. Bone E. None of these @ Kidney - ' 24. A megakaryocyte ~ \/A. Can give rise to a platelet B. Can give rise to a lymphocyte C. Can give rise to a lymphocyte D. 'All of these E. Two of these 25. A metabolite of the pyrolle rings \/ A. Urobilinogen D. All of these ‘K B. Hemosiderin EB). Two of these / C. Biliverdin _, 26. The liver ’ \/ A. Activates Vitamin D D. All of these KB. Make gamma globulin ' I Two of these JC. Makes urea 27. “Food” coming from thedigestive system would normally be found in the \/A. The hepatic portal vein V . D. All of these KB. The canaliculi {l3 Two of these J C. The sinusoids . 28. Micelles )QA. Help emulsify fats All of these / B. Are make from bile salts ' E. Two of these /C. Are soluble in Water 29. 30. 31. 32. 33. 34. 35. The intrinsic pathway /A. Forms Factor X - \/B. Is the way a thrombus forms / C. Has more steps in it than the extrinsic pathway (1). All of these E. Two of these Fibrino gen / A. Is made in the liver >CB. Requires Vitamin K to be made / C. Is more concentrated in the efferent arteriole than the afferent arteriole D. All of these Two of these Dissolves clots . Plasmin/ B. Heparin C. .Coumadin D. All ofthese E. Two of these He atitis caused by contaminated body fluids . HCV D. Allofthese B. HEV E. Two ofthese C. HAV ' Tessalon is a A. An expectorant ® An antitussive C. A drug used in asthma therapy D. An antihistamine E. Amucolytic Structures derived from the adenohypophysis ~ X A. Produce releasing hormones K B. Produce oxytocin KC. Store and release oxytocin @ None of these E. Two ofthese Corticotrophs _ \/ A. Are found in the adenohypophysis { B. Produce ACTH / C. Produce MSH (D. AllOfthese E. Two ofthese A= INCREASE OR GREATER THAN B=DECREASE OR LESS THAN C=NO EFFECT OR EQUAL TO Fr 36. The effect of angiotensin II on thirst i5 37. The effect of angiotensin II on the renal clearance of sodium C 38. The concentration of creatinine in the afferent arteriole as compared its concentration in the efferent arteriole. B 39. The concentration of FSH in the afferent arteriole as compared to its concentration in the efferent arteriole. " h 40. The amount of inulin in the renal artery as compared to the renal vein. C 41. The amount of inulin in Bowman’s capsule as compared to the amount in the collecting duct. f5 42. The amount of PAH in Bowman’s capsule as compared to the amount in the collecting duct. 1% 43. The hematocrit in the afferent arteriole as compared to the hematocrit in efferent arteriole [ 44. The amount of glucose secreted as compared to the amount of glucose in the collecting duct. C 45. The amount of glycine in the descending loop of Henle as compared to the amount of glycine in the ascending loop of Henle. , ’ C 46. The effect of aldosterone on the concentration of potassium in the afferent arteriole as compared to the efferent arteriole. ‘ A 47. Assuming equal concentrations in renal artery, compare the concentration of inulin to the concentration of PAH in the renal vein. ' r 7. A 48. The effect of stimulating the nucleus tractus solitarius on the subsequent activity of the external intercostals. 49. The effect of a lack of surfactant on the magnitude of intra—alveolar pressure at the end of inspiration. 50. The effect of a lack of surfactant on the likelihood of atelectasis. lO g 51. The magnitude (absolute value) of inter—pleural pressure as compared to the magnitude of intra—alveolar pressure during expiration. 52. The magnitude of the'tidal volume as compared to the FEV-l C 53. The p02 in the pulmonary vein as compared to the p02 in the alveolus C 54. The pCng in the renal artery as compared to the 1:92 in the renalvein. A 55. The effect of the Bohr effect on the p50 of hemoglobin {\ 56. The number of neutrophils as compared to the number of lymphocytes l5 57. The desirability of havingléfi’s versus the desirability of having PHDL’S E 58. The effect of prostacyclins on platelet aggregation; C 59. The effect of stimulating the osmoreceptors on the amount of ADH secreted into the primary plexus. ' L 60. The effect of prolactin on milk let down C 61. The effect of MSH on melatonin secretion (>62. The effect of growth hormone on plasma glucose levels A 63. The effect of growth hormone on beta oxidation 64. The effect of IGF’s on growth hormone secretion ‘5 65. The effect of somatostatin on growth hormone secretion. 11 .udent : ‘tructo ;t Vers 3 ;tion Number :ed Question (*) - Answers (*=Multiple) 'ect Answer(s) : question deleted aqt=22fifi qOS‘IX 805-10 '70g' ]% $05 '“9 ago '1‘ Auburn University Test Scoring 04/14/05 Student's Summary ID: Test Date: 04/11/05 Course: BIOLSSOO Test Time: :00 Raw Score: 90.5% 57 L Percent: Mo; 5 5 5 1...5....0....5....0....5....0....5....0....5....0....5....O....5 1 * a i- ** ECECDDBDEDEEEEEAEBCADBCAEEEEDEAABDDAECBACBBCCCAACCBBCCAABBCCCBACB ECDKBDBDEDCEEEEAEfiCADACAEEEEDEAAEDDABCEACBBCCCAACABECCAABBCCCAAEE ' E *7: ...
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Test 3 Mammalian - ' 5 Put your name on the front and on...

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