BIO 20- Inheritance 2WEB - Lecture Outline Lab 5...

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1 11/14/2008 1 20 Inheritance 2: November 17 11/14/2008 2 Lecture Outline • Lab 5 Crickets—Dr. Kevin Judge • Molecular basis for dominance (Freeman Ch 13 282-283) • Sex determination & sex-linked inheritance (Freeman Ch 13 276-278) 11/14/2008 3 Final exam Monday, December 8 4-7pm https://registrar.utm.utoronto.ca/student/exa mschedule/finalexams.php •RAWC Gym ( A-Ml ) • SE Gym ( Mo-Z ) 11/14/2008 4 Facilitated Study Groups Monday: 11:00 A.M - 12:00 SB3007 Thursday: 12:00 - 1:00 P.M. CCT 2134
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2 11/14/2008 5 Sexual selection and the Cricket Powerpoint slides (and video clip) on Bb in Lab 5 folder 11/14/2008 6 1. Molecular basis of dominant & recessive traits Remember: DNA RNA protein Mutant allele [often] defective product Mutation— blocks or decrease the amount of the the synthesis, or destroys the functional activity of a protein loss of function Often mutant alleles are recessive “50% of the normal protein is enough” 11/14/2008 7 Incomplete dominance 11/14/2008 8 Pattern: • 3 phenotypes in the F 2
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3 11/14/2008 9 What is the molecular explanation? “R” is a gene which codes for an enzyme which produces a colour pigment. “r” is a gene which codes for a dysfunctional enzyme so no colour pigment is produced “Rr” heterzygote genotype only a small amount of pigment if produced 11/14/2008 10 Co-dominant e.g., blood groups MN MN gene codes for membrane protein on red blood cells in humans Phenotype indicates the type of membrane protein present Typically 2 types of alleles—code for either the M or N protein Genotypes MM NN or MN Phenotype M or N or MN 11/14/2008 11 ABO blood types 11/14/2008 12 ABO: co-dominant
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This note was uploaded on 04/25/2010 for the course BIO BIO152 taught by Professor Cordon during the Fall '09 term at University of Toronto- Toronto.

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BIO 20- Inheritance 2WEB - Lecture Outline Lab 5...

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