BIO 21-HardyWeinbergWEB - LAB HELP next week (Nov 24-28)...

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1 11/19/2008 1 21- Hardy Weinberg Equilibrium Allele & Genotype Frequencies Lecture 21 Wednesday November 19 th LAB HELP next week (Nov 24-28) ± Tuesday 11-1pm SB1085 Geeta Wednesday 2-4 pm [ upstairs in SB4073 ] Jessica Thursday 10-12 noon SB1085 Jessica ± Thursday 2-4pm [ upstairs in SB4073 ] Jessica Friday 11-1 SB1085 Geeta Friday 1-3pm SB1085 Nav ± Friday 3-5pm SB1085 Nav 11/19/2008 3 Outline ± Finish—sex-linked inheritance ± Hardy-Weinberg model ± Try this flash simulation http://zoology.okstate.edu/zoo_lrc/biol1114/tutorials/Flash/life 4e_15-6-OSU.swf Freeman Ch 25.1 and Freeman tutorial 25.1 11/19/2008 4 Evolution Evolution is the descent with modification of organisms related by common ancestry. We have talked about the ± adaptive process of natural selection and ± random process of genetic drift the change in allele frequency over time .
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2 11/19/2008 5 Understanding Evolution How do we tell if evolution has happened? How do we tell if evolution has NOT happened? What should we expect to see in the allele frequency? 11/19/2008 6 Change in allele frequency if evolution has happened , then the allele frequencies should change over time if evolution has NOT happened, then the allele frequencies should remain the same (no change) 11/19/2008 7 Gene Pool ± Individual members of a population contribute their alleles to a common pool of genes. www.brooklyn.cuny.edu/bc/ahp/ AD/C21/C21_GenePool.html 11/19/2008 8 All the alleles in a population (a group Of interbreeding organisms) are part of A GENE POOL These alleles are relatively stable i.e. they do not change by themselves, there must be an “agent” to cause them to change (LD)
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3 11/19/2008 9 Hardy Weinberg principle allele frequencies & therefore genotype ratios in a randomly-breeding population remain constant from generation to generation that is, they remain in EQUILIBRIUM Thus, Mendelian genetics implies that genetic variability can persist indefinitely, unless other evolutionary forces act to remove it. 11/19/2008 10 Hardy-Weinberg (1908) theorem If only random mating occurs, then allele frequencies remain unchanged over time .
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This note was uploaded on 04/25/2010 for the course BIO BIO152 taught by Professor Cordon during the Fall '09 term at University of Toronto- Toronto.

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BIO 21-HardyWeinbergWEB - LAB HELP next week (Nov 24-28)...

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