6720 Lecture 11_nuclear imaging

6720 Lecture 11_nuclear imaging - Lecture XI 1 2 3 4 5...

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1 PHYS 6720 - Lecture XI 1 Lecture XI Nuclear Imaging 1. Molecular imaging and source 2. Gamma camera 3. PET 4. SPECT 5. PET/CT and SPECT/CT PHYS 6720 - Lecture XI 2 XI-1 Nuclear Imaging and Source Nuclear imaging γ -ray photons (~1MeV) from radioactive (unstable) nuclei or radionuclides. Deep penetration through soft and hard tissues. Functional imaging due to the uptake of the radioactive “drug” or radiopharmaceuticals by molecules Æ established molecular imaging modalities (PET, PET/CT, SPECT/CT). Tomography capable Æ also called emission computed tomography (ECT) Used for perfusion imaging in heart, brain, lungs; tumor detection through hypermetabolic activity and specific antibody; diagnosis of organ function in thyroid, kidneys, liver; density and condition of neurotransmitters in brain PHYS 6720 - Lecture XI 3 XI-1 Nuclear Imaging and Source Nuclear imaging SPECT = Single Photon Emission Computerized Tomography PET = Positron Emission Tomography Tomography capable Æ also called emission computed tomography ( ECT ) γ -ray photons (~1MeV) from radioactive (unstable) nuclei or radionuclides. Deep penetration through soft and hard tissues. Functional imaging due to the uptake of the radioactive “drug” or radiopharmaceuticals by molecules Æ established molecular imaging modalities (PET, PET/CT, SPECT/CT). PHYS 6720 - Lecture XI 4 XI-1 Nuclear Imaging and Source Nuclear imaging Used for perfusion imaging in heart, brain, lungs; tumor detection through hypermetabolic activity and specific antibody; diagnosis of organ function in thyroid, kidneys, liver; density and condition of neurotransmitters in brain Require nuclear reactors Low spatial resolution due to the lack of compact detectors for γ -ray photons PHYS 6720 - Lecture XI 5 XI-1 Nuclear Imaging and Source Nuclear imaging Functional / molecular imaging but with poor resolution PHYS 6720 - Lecture XI 6 XI-1 Nuclear Imaging and Source Deep penetration Attenuation coefficient in water
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2 PHYS 6720 - Lecture XI 7 XI-1 Nuclear Imaging and Source
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6720 Lecture 11_nuclear imaging - Lecture XI 1 2 3 4 5...

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