{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Chapter 16 lecture

Chapter 16 lecture - Saturday 4PM 1171 Tuesday Feb 16 4-5PM...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
Saturday 4PM 1171
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Tuesday Feb. 16 , 4-5PM, PSBN 4606 Dr. Koby Levy, Weizmann Institute “Post-Translational Modifications: Biophysics and Evolution” Wednesday Feb. 24 , 11-12, MRL 2053 Dr. Celia Goulding, UC Irvine "Discovery of a unique mycobacterial heme uptake system: A structural and biochemical study"
Background image of page 2
Chapter 16: The Citric Acid Cycle
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Only a Small Amount of Energy Available in Glucose is Captured in Glycolysis 2 G’° = -146 kJ/mol Glycolysis Full oxidation (+ 6 O 2 ) G’° = -2,840 kJ/mol 6 CO 2 + 6 H 2 O GLUCOSE
Background image of page 4
Aerobic conversion of glucose to CO 2 and H 2 0 (respiration)….three stages Chapter 19 Chapter 17 Chapter 18 evolutionary origin: 2.5 billion years ago used by animals, plants, and many microorganisms Occurs in mitochondria glycolysis/cytosol; stage 3/mitochondrial membrane
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Background image of page 6
Pyruvate Dehydrogenase Complex (PDC) PDC is a large ( M r = 7.8 × 10 6 Da) multienzyme complex - pyruvate dehydrogenase (E 1 ) - dihydrolipoyl transacetylase (E 2 ) - dihydrolipoyl dehydrogenase (E 3 ) short distance between catalytic sites allows channeling of substrates from one catalytic site to another channeling minimizes side reactions activity of the complex is subject to regulation (ATP)
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
The three enzyme pyruvate dehydrogenase complex (PDH)… multiple copies within these structures mammalian
Background image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}