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Unformatted text preview: embryonic germ cells o EGS isolated from fetus @ 5-9 weeks Ethical Issues! Embryonal Carcinoma Cell ( EC ) = a type of cancer caused by primordial germ cells that have b/cm cancerous o Primordial Germ Cell = PGC = migrate to gonadal ridge & grows into germ cells (sperm/egg) o EGC , ESC and PGCs are all pluripotent Types of Embryonal Carcinoma Cells (ECC) 1960/70s found teratocarcinomas in mice testes had tissues from all 3 germ layers suggest primordial germ cells are pluripotent Abnormal Chromosome # !!!! Ways of Create ECCs o Take primordial germ cells from developing fetus inject/transplant into testes of adult mice Q) Can we make teratocarcinomas by injecting PGCs into skin/other body part of mice? o Take embryonic cells inject into skin of adult mice...
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- Spring '09