LS3-11-10 - Lecture 11 Viruses Bacteriophage Influenza...

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Lecture 11 Viruses Bacteriophage Influenza Human Immunodeficiency Allison p48-52
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Viroids Small Circular single-stranded RNA 250 – 400 nt; no protein encoded Lethal disease in Avocado & Coconut Prions Infectious Protein agents structurally modified Lethal slow diseases Mad Cow Disease Scrapie (sheep) Kuru, Creutzfeld-Jacob disease (humans) Molecules as Infectious Agents
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Viruses Simplest form of organism Obligate Intracellular Parasites - grow within the cells of another organism - HOST Specificity Cannot replicate on their own - must subvert the translation machinery of the host cell
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Virion = one virus particle GENOME = DNA or RNA • Single- or Double-stranded • Linear or Circular CAPSID = Protein Coat Assembled from multiple copies of one or a few proteins Lipid coat
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Some viral capsids are covered with a membrane or envelope. Derived from the host cell membrane Contains viral proteins (spikes) Herpes virus Symmetric capsid Influenza Virus No regular capsid
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The Virus Zoo DNA vs. RNA Double Stranded vs. Single Stranded Circular vs. Linear Segmented or Not Plus Strand vs.
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