Lecture 3 - Synaptic Transmission Chemical Transmission of...

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Synaptic Transmission: Chemical Transmission of Signals from One Neuron to Another Structure of Synapses Most common o Axodendritic – axons on dendrites o Axosomatic – axons on cell bodies Dendrodendritic – capable of transmission in either direction Axoaxonal – maybe involved in presynaptic inhibition Neurotransmitter A chemical stored in “vesicles” of the presynaptic neuron, which, when released into the synaptic cleft, influences the activity of the postsynaptic neurone The neurotransmitters: o Small-molecule neurotransmitters o Amino Acid neurotransmitters o Monoamines o o Neuropeptides (Opiates) Neurotransmitter molecules o o Large – Assembled in the cell body, packaged in vesicles & then transported to the axon terminal Exocytosis – the process of NT release The arrival of an AP at the terminal opens voltage-activated Ca 2+ channels The entry of Ca
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Lecture 3 - Synaptic Transmission Chemical Transmission of...

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