BIS 104 PQ 8 Spring 2010

BIS 104 PQ 8 Spring 2010 - Describe how(an experiment you...

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BIS 104 PQ 8 Spring 2010 8. It has been hypothesized that some human breast cancers arise when breast epithelial cells begin to express abnormally high levels of a growth factor receptor, erbB2, on their plasma membranes. The erbB2 molecule is a transmembrane protein with an external domain that serves as the binding site for the epidermal growth factor (EGF) ligand.
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Unformatted text preview: Describe how (an experiment ) you would use the technique of immunocytochemistry (ICC) to test the hypothesis that human breast cancer cells over-express erbB2 protein as compared to normal breast epithial cells. Describe the results you would expect to observe if the hypothesis were shown to be correct. EXPERIMENT: RESULTS:...
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