corSegment_24 - TheMajorHistocompatibility Complex Discuss...

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The Major Histocompatibility  Complex Discuss the inheritance and expression of MHC molecules.
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Then: You will understand why finding a match for an organ transplant is so difficult. You will know the probability that your parent or a sibling would be able to donate a kidney to you, if you needed one.
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MHC Molecules Encoded in a large genetic locus called the Major Histocompatibility Complex (MHC) Multiple MHC class I and II molecules are encoded in the MHC. Other critical immune system components are also encoded in the MHC (C’, cytokines, proteins involved in antigen presentation). These are called MHC class III genes. Mouse MHC is named H-2. Human MHC is named HLA.
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Diversity in MHC Molecules Two components: 1. Gene Families:  multiple similar genes encoding MHC  Class I and MHC Class II molecules. [The products of  the different genes in a MHC Class I or Class II family  are called  isotypes .] 1. Genetic Polymorphism: multiple alternative forms of a 
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corSegment_24 - TheMajorHistocompatibility Complex Discuss...

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