segment_5_overview_adaptive_immunity_II

segment_5_overview_adaptive_immunity_II - Adaptive Immunity...

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4/28/10 Adaptive Immunity Humoral Immunity (Antibody) Delayed Hypersensitivity T cell-mediated cytotoxicity All pathogens; Extracellular bacteria Intracellular bacteria Viruses
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4/28/10 Adaptive Immunity has: 1. Antigenic specificity: receptors on lymphocytes recognize (bind to) molecular structures unique to the invading pathogen and not found on either self cell or molecules or on other pathogens. These are called epitopes.
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4/28/10 Antigen: foreign substance that elicits an immune response. “Ag” Epitope: part of Ag that contacts receptor. i.e. Antigenic determinant. An antigenic molecule, such snake venom, can possess multiple epitopes that can be recognizes by the immune system…each epitope by a different lymphocyte. Two Related Terms
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4/28/10 Adaptive Immunity has: 1. Antigenic specificity 2. Diversity: random assortment of antigen receptor gene segments allows for the generation of many different antigen receptor molecules. Each lymphocyte uses only one combination of gene
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segment_5_overview_adaptive_immunity_II - Adaptive Immunity...

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