segment_9 - Phagocytosis Pore formation is also regulated...

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Many bacteria release proteases to facilitate the invasion of tissue.
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Complement: The central (and critical) reaction is the cleavage of C3 into C3b and C3a.
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There are three pathways leading to the cleavage of C3.
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Complement activation must be regulated so that invading bacteria are killed but not healthy tissue cells.
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Opsonization and Destruction of Bacteria by
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Unformatted text preview: Phagocytosis Pore formation is also regulated to prevent lysis of healthy tissue. C3a and C5a act as chemokines to recruit phagocytic cells to the site of infection. They are also some times referred to anaphylatoxins due to their ability to trigger mast cell degranulation and release of vasoactive mediators....
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segment_9 - Phagocytosis Pore formation is also regulated...

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