segment_26 - B cell Development Cell-cell interactions...

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  Phases of B cell Development and Differentiation
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Phase 3:  Migration of B  cells from primary to  secondary lymphoid tissues   where they compete for the  limited number of sites in the  follicles.  They complete their  maturation to full  immunocompetence in the  follicles.
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Surface markers on Developing B cells.
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Ig Genetic Locus at each stage of
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Unformatted text preview: B cell Development Cell-cell interactions during B cell Development Sequence of Heavy Chain Gene Rearrangement The Pre-B cell Receptor Allelic Exclusion Affinity: tightness of binding of an antigen-binding pocket to the epitope Avidity: affinity plus valency leads to tighter binding of antibody to the antigenic molecule/particle....
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This note was uploaded on 04/27/2010 for the course MMG 451 taught by Professor Brooks during the Spring '08 term at Michigan State University.

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segment_26 - B cell Development Cell-cell interactions...

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