segment_31 - made in secondary lymphoid tissue • The...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 8 T Cell-Mediated Immunity Copyright © Garland Science 2009
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Morphological  Changes in Dendritic  Cells as They Migrate  to the Draining Lymph  Node.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Toll-like Receptor Expression and Dendritic Cell Function   Dendritic cells carry all of the TLRs except TLR9.    Signals from TLRs activate dendritic cells.    TLR stimulation leads to increased  peptide presentation  on MHC class II.   Expression of CCR7 the receptor for CCL21, which is 
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: made in secondary lymphoid tissue. • The CCR7/CCL21 mediated signal causes the dendritic cell to stop taking up and processing antigen, but rather to present peptides to the T cells. • This signal also increases MHC class I and II expression leading to long-lived peptide/MHC complexes on the surface of the mature dendritic cell. Role of Adhesion Molecules in T cell Entry into Secondary Lymphoid Tissues...
View Full Document

This note was uploaded on 04/27/2010 for the course MMG 451 taught by Professor Brooks during the Spring '08 term at Michigan State University.

Page1 / 10

segment_31 - made in secondary lymphoid tissue • The...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online