segment_54 - Chapter 11 Garland Science 2009 Failures of...

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Inherited immunodeficiency diseases Rare primary immunodeficiency diseases reveal how the human immune system works Inherited immunodeficiency diseases are caused by dominant, recessive, or X-linked gene defects Chapter 11 © Garland Science 2009 Failures of the Body’s Defenses
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Antibody deficiency leads to an inability to clear  extracellular bacteria Diminished production of antibodies also results  from inherited defects in T-cell help Defects in complement components impair  antibody responses and cause the accumulation  of immune complexes
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Unformatted text preview: Chapter 11 Garland Science 2009 Failures of the Bodys Defenses Defects in phagocytes result in enhanced susceptibility to bacterial infection Defects in T-cell function result in severe combined immune deficiencies Some inherited immunodeficiencies lead to specific disease susceptibilities Chapter 11 Garland Science 2009 Failures of the Bodys Defenses Transplantation of hematopoietic stem cells is used to correct genetic defects of the immune system Chapter 11 Garland Science 2009 Failures of the Bodys Defenses...
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segment_54 - Chapter 11 Garland Science 2009 Failures of...

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