segment_63 - hormones Chapter 13 © Garland Science 2009...

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©  Garland Science 2009 C C hapter 13: hapter 13: Disruption of Health Disruption of Health Tissue by the Immune Tissue by the Immune Response Response
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Autoimmune diseases In healthy individuals the immune system is tolerant  of self antigens Autoimmune diseases are caused by the loss of  tolerance to self antigens Chapter 13 ©  Garland Science 2009 Disruption of Healthy Tissue by the Immune Response
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The effector mechanisms of autoimmunity  resemble those causing hypersensitivity  reactions Chapter 13 ©  Garland Science 2009 Disruption of Healthy Tissue by the Immune Response
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Endocrine glands contain specialized cells  that are targets for organ-specific  autoimmunity Chapter 13 ©  Garland Science 2009 Disruption of Healthy Tissue by the Immune Response
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Autoimmune diseases of the thyroid can cause either  underproduction or overproduction of thyroid 
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Unformatted text preview: hormones Chapter 13 © Garland Science 2009 Disruption of Healthy Tissue by the Immune Response • Ectopic lymphoid tissue can form at sites inflamed by autoimmune disease Chapter 13 © Garland Science 2009 Disruption of Healthy Tissue by the Immune Response • Type 1 diabetes is caused by the selective destruction of insulin-producing cells in the pancreas Chapter 13 © Garland Science 2009 Disruption of Healthy Tissue by the Immune Response • Autoantibodies against common components of human cells can cause systemic autoimmune disease Chapter 13 © Garland Science 2009 Disruption of Healthy Tissue by the Immune Response • Most rheumatological diseases are caused by autoimmunity Chapter 13 © Garland Science 2009 Disruption of Healthy Tissue by the Immune Response...
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