segment17abasAg - Antibodies Can Be Antigens What? Types of...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
Antibodies Can Be Antigens Types of Ab epitopes: 1. Isotypic determinants; isotype . 2. Allotypic determinants; allotype . 3. Idiotypic determinants; idiotype . What?? Epitopes are also called antigenic determinants.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Immunize with human IgM Makes mouse anti-human IgM
Background image of page 2
Immunize with human IgG Makes mouse anti-human IgG
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Antibodies Can Be Antigens Types of Ab epitopes: 1. Isotypic determinants; isotype . 2. Allotypic determinants; allotype . 3. Idiotypic determinants; idiotype . What??
Background image of page 4
Mouse A IgM A B Anti- mouse ‘A’ IgM
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Antibodies Can Be Antigens Types of Ab epitopes: 1. Isotypic determinants; isotype . 2. Allotypic determinants; allotype . 3. Idiotypic determinants; idiotype . What??
Background image of page 6
Anti-circle IgG Anti-triangle IgG Anti-(anti-circle IgG) antibody immunize
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Antibodies to other antibodies or cytokines or surface proteins or pathogens are often very useful in designing assays for diseases or assaying the functionality of the immune system. They can also be used to therapeutically treat diseases. For example, mouse anti-CD3 was used to prevent T cell-mediated
Background image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/27/2010 for the course MMG 451 taught by Professor Brooks during the Spring '08 term at Michigan State University.

Page1 / 13

segment17abasAg - Antibodies Can Be Antigens What? Types of...

This preview shows document pages 1 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online