BME 210 Lecture 1 Cells and Biomolecules

BME 210 Lecture 1 Cells and Biomolecules - BME-210 –...

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BME-210 Engineering Biology 1. Introduction Blackboard Vista Class policies Course concept Cells and Bio-molecules
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BME 210 on BlackBoard Vista Go to BlazerNet: blazernet.uab.edu To bypass BlazerNet: www.uab.edu/academiccourses Login Go to Courses and Training , then Student Dashboard area Go to BME 210 Open Course Content
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Instructor: Dr. Vladimir Fast Time: Monday, Wednesday, 10:00-11:15 Location: HOEN 120 Office: 1670 University Blvd., VH B126 Phone: 975-2119 e-mail: fast@crml.uab.edu Office hours: By appointment Required textbooks: None Recommended books: Methods in Modern Biophysics, Bendt Nölting, Springer, 2006 Prerequisite: BY 123 Co-requisite: BY 116 (or BY 210), PH 222 Course Description: This course will focus on how engineering is used to investigate biological systems at the cellular and molecular levels. The course will include a review of traditional methods used for biological investigations as well as of emerging technologies in the fields of biotechnology and nanotechnology Covered topics: Overview of cells and bio-molecules Methods for imaging cells and molecules: optical microscopy, fluorescence microscopy, electron microscopy, tunneling microscopy, atomic force microscopy Methods for separation of cells and bio-molecules: flow cytometry, cell culture, centrifugation, chromatography, electrophoresis, blotting Methods for DNA studies: X-ray diffraction, sequencing, PCR Methods for protein studies: X-ray crystallography, NMR spectroscopy, mass spectrometry, surface plasmon resonance Genomics and proteomics: DNA and protein microarrays Emerging technologies: nanotechnology, lab-on-a-chip systems, synthetic biology Syllabus: BME 210 – Engineering Biology
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4 tests: Closed notes. No computers, calculators or other electronic devices are allowed Questions: multiple choice, short answer, brief description, drawing of simple diagrams Missed test can be made up only with a signed medical excuse or under special circumstances Grading: Each test – 25% points Grade will be normalized by the common average Total of 100 points: 90-100 – A 80- 89 – B 70- 79 – C 60- 69 – D <59 – F Tests and grading
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Schedule (tentative) 1 W 1/6 Class policies. Introduction. Cells; Biomolecules 2 M 1/11 Imaging of cells and biomolecules . Optical microscopy 3 W 1/13 Optical microscopy; Fluorescence microscopy M 1/18 Martin Luther King Day 4 W 1/20 Fluorescent dyes; Immunofluorescence; FISH 5 M 1/25 Fluorescent quantum dots 6 W 1/27 GFP; FRET 7 M 2/1 Confocal microscopy W 2/3 Test 1 8 M 2/8 Calcium imaging 9 W 2/10
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This note was uploaded on 04/28/2010 for the course BME 210 taught by Professor Fast during the Spring '10 term at University of Alabama at Birmingham.

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BME 210 Lecture 1 Cells and Biomolecules - BME-210 –...

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