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Unformatted text preview: 1 112A Biomechanics Final Review of Book Chapters Note: This is just a review of book chapters; it does not include lectures (although, of course there is some overlap). This handout is only to be used as a study guide, and is not necessarily indicative of what will appear on the final exam. An answer key will not be provided; however, I will post the chapter sections where the problems came from on Sunday. ** Please try to fill this out on your own before consulting others and/or the book.** If you can solve all (ideally!) or most of the problems on your own, you are probably in good shape for the test (assuming you have gone over lectures and HW, too). Good luck! ~Jennifer 1.) What is the relation between transmural pressure, surface tension and principal radii of curvature r1 and r2 for the surface of a liquid column in a capillary tube standing in a bath? Assume the surface tension is constant in every direction. Hint: This is the Law of Laplace! 2.) What is the relation when the surface tension is not constant in every direction? For this relation, what is the requirement for membrane thickness? 3.) If the membrane is thick (what are some biological examples?), is the stress uniformly distributed in the wall? What new relation must be used for this case (of a cylinder and a spherical shell)? You should know how to derive these relationswe did it in 110. 4.) What are the contents of human blood (know approximate weight percents of components)? 5.) Draw a RBC with approximate dimensions. 2 6.) Blood viscosity can be measured in a Couetteflow viscometer (make sure you can describe this). Plot viscosity vs. shear rate of whole blood (Hct=90% and Hct = 45%) and plasma. Know approximate values for each axis (order of magnitude is sufficient). How does temperature affect the graphs? 7.) At very low shear rate (i.e. 0 to 3 ), what important relation for blood shear stress was discovered by Cokelet et al.? Please plot the graph and state the equation. How does blood behave at high shear rate and what equation do you use to relate stress, strain rate and viscosity?...
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This note was uploaded on 04/30/2010 for the course BENG 112A taught by Professor Mcculloch during the Winter '09 term at UCSD.
 Winter '09
 MCCULLOCH

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