antimicrobial document

antimicrobial document - Jundishapur Journal of...

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Jundishapur Journal of Microbiology (2010); 3(1): 10-14 10 Jundishapur Journal of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Phone: +98611 3330074; Fax: +98611 3332036; URL: http://jjm.ajums.ac.ir; E-mail: editorial office: jjm@ajums.ac.ir Original article Antimicrobial activity of essential oils of Ferulago angulata subsp. carduchorum Mojtaba Taran 1 , Hamid Reza Ghasempour 2 , Ebrahim Shirinpour 2 1 Microbiology Laboratory, Biology Department of Razi University, Kermanshah, Iran 2 Plant Tissue Culture, Biotechnology and Physiology Laboratory, Biology Department of Razi University, Kermanshah, Iran How to cite this article: Taran M, Ghasempour HR, Shirinpour E. Antimicrobial activity of essential oils of Ferulago angulata subsp. carduchorum . Jundishapur J Microbiol. 2010; 3(1): 10-14. Received: October 2009 Accepted: December 2009 Abstract Introduction and objective: Ferulago angulata is an important medicinal plant of Iran. The essential oil of seeds aerial parts of this plant contains variety of components with different therapeutical effects. The purpose of this study was to provide the first examination of the antibacterial and antifungal effects of essential oils obtained from aerial parts and seeds of F. angulata subsp. carduchorum which is endemic to Shahoo Mountains (west of Iran). Materials and methods: Chemical composition of the essential oils of seeds and aerial parts of F. angulata subsp. carduchorum was analysed by the Gas Chromatography-mass spectrometry (GC-MS). The susceptibility of the microorganisms to essential oils was determined by minimum inhibitory concentration (MIC) using microdilution method. Results: The GC-MS analysis of the essential oils has led to the identification and quantification of 57 components, the most abundant of them were cis-ocimene (27.9%) for aerial parts and α -pinene (76.1%) for seeds. Other compounds present ( α -pinene, β -pinene, 4-terpineol, α -terpineol and caryophyllene oxide) have been reported to have antimicrobial effects on bacteria and fungi. Among different bacteria, Staphylococcus aureus (MIC= 15μg/ml) and Listeria monocytogenesis (MIC=137μg/ml) disclosed a high sensitivity to essential oils of aerial parts and seeds respectively. These essential oils showed weak activity against fungus ( Candida albicans ). Conclusion: This study showed that the essential oil of seeds and aerial parts of F. angulata subsp. carduchorum have antimicrobial activity against different infectious microbes. Keywords: Ferulago angulata , Antifungal, Antibacterial, Essential oil Introduction The genus Ferulago belongs to Apiaceae family [1]. Ferulago species are used in folk medicine for their sedative, tonic, digestive and anti-parasitic effects [2,3]. Antibacterial and antifungal activities have
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antimicrobial document - Jundishapur Journal of...

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