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BMB461-07-_Exam_IV_Form_A_-_Answers - Your Name BMB461 Exam...

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Your Name: This is Form A of the exam. Please mark on your scoring sheet. 1 BMB461 Exam IV, 12-10-2007 The exam begins at 8:40am and finishes at 9:30am sharp. The time needed to fill in the scoring sheet is included. Boxes will close at 9:35. Important, please note on the bottom of the page the form number for this particular exam and mark it in the form box on the scoring sheet. 30 questions are worth 3 points each; 5 are worth 2 points as indicated. Each question has only a single correct answer. 1. Mark the one incorrect statement about the pyruvate dehydrogenase reaction: A. Hydroxyethyl thiamine pyrophosphate (TPP) is an intermediate. B. Oxidized lipoyllysine is an intermediate. C. Acetyl-CoA is a product. D. Pyruvate is a substrate. E. Carbon dioxide is released. F. NADH is a product. G. FADH 2 is released. XXXXX 2. Name the structure shown on the right? A. coenzyme A (CoA) XXXXX B. lipoyllysine C. biotin D. thiamine pyrophosphate (TPP) E. ATP F. FADH 2 G. NADH 3. What statement is incorrect about the subunits of the pyruvate dehydrogenase complex? A. E2 is the dihydrolipoyl transacetylase. B. E1 is the pyruvate dehydrogenase. C. E3 is the dihydrolipoyl dehydrogenase. D. All three cooperate to accomplish substrate channeling. E. They from a large multi subunit complex. F. E1 contains a rotating dihydrolipoyl arm. XXXXX G. The dihydrolipoyl dehydrogenase is a flavoprotein. 4. In which carbon of which TCA cycle intermediate is carbon 1 of pyruvate found during the first round of the cycle? A. none XXXXX B. the prochiral carbon of citrate C. carbon 1 of α -ketoglutarate D. carbon 2 of citrate E. the 4-methylene carbon of α -ketoglutarate F. carbon 5 of α -ketoglutarate
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This is Form A of the exam. Please mark on your scoring sheet. 2 5. In the forward reactions of the TCA cycle in mitochondria the following compound is the product of the reaction catalyzed by: A. Isocitrate lyase B. Citrate synthase C. α -Ketoglutarate dehydrogenase D. Isocitrate dehydrogenase E. Aconitase XXXXX F. Succinyl-CoA synthetase G. Malate dehydrogenase 6. Prochirality of a symmetrical substrate molecule leads to its asymmetric binding to which TCA cycle enzyme? A. Citrate synthase B. Aconitase XXXXX C. Isocitrate dehydrogenase D. α -Ketoglutarate dehydrogenase E. Succinyl-CoA synthetase F. Succinate dehydrogenase G. Malate dehydrogenase 7. Which of the TCA cycle enzymes produce NADH in the forward direction? 1) Citrate synthase, 2) Aconitase, 3), Isocitrate dehydrogenase, 4), α -Ketoglutarate dehydrogenase, 5) Succinyl-CoA synthetase, 6) Succinate dehydrogenase, 7) Fumarase, 8) Malate dehydrogenase A. 3,4,6,8 B. 3,4,8 XXXXX C. 4,6,8 D. 3,6,8 E. 3,4,7,8 F. 1,4,8 G. 3,6,8 8. Which of the enzymes of the cycle shown below to the right have isoforms in the TCA cycle? 1) Citrate Synthase, 2) Aconitase, 3), Isocitrate lyase, 4), Malate synthase 5) Malate Dehydrogenase A. 1,2,3,4 B. 1,2,3 C. 1,3,4 D. 1,2,4 E. 1,2,5 XXXXX F. 1,3,4,5 G. 3,4 9. After which defining intermediate is the cycle to the right named? A. Acetyl CoA
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BMB461-07-_Exam_IV_Form_A_-_Answers - Your Name BMB461 Exam...

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