SP 2010_-_Topoisomerase

SP 2010_-_Topoisomerase - - relaxes negative supercoils...

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a tyrosine (Y) residue -- attack a phosphate. When the strand is cleaved, it rotates around the other strand. It is age of both strands of the G segment and the binding of an additional DNA duple, the T segment. This T segm Topoisomerase 1. type I topoisomerase - cleave one strand of the DNA -- can de catenate two ssDNA circles a. type 1A
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Unformatted text preview: - relaxes negative supercoils only • strand passage mechanism b. type 1B- relaxes both positive and negative supercoils • controlled rotation mechanism type II topoisomerase - cleave two strands of DNA -- relaxes positive and negative supercoils, can induce negative supercoils, can de catenate two dsDNA circles...
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This note was uploaded on 05/03/2010 for the course CHEM Chem 114C taught by Professor Hoffman during the Spring '07 term at UCSD.

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SP 2010_-_Topoisomerase - - relaxes negative supercoils...

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