SP 2010_-_Chemical Mutagen

SP 2010_-_Chemical Mutagen - - in which one or more...

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Chemical Mutagen (damage + replication = mutation) point mutations - in which one base pair replaces another o transitions - A=G, C=G oxidation deamination base analogs o transversion - purine is replaced by pyrimidine or vice versa alkylating agents examples : nitrogen mustard, ethylnitrosourea, and MNNG insertion/deletion
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Unformatted text preview: - in which one or more nucleotide pairs are inserted in or deleted from DNA • thymine/pyrimidine dimers o induced by UV radiation which promotes the formation of a cyclobutyl ring between adjacent thymine residues on the same DNA strand to from an intrastrand thymine dimer...
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This note was uploaded on 05/03/2010 for the course CHEM Chem 114C taught by Professor Hoffman during the Spring '07 term at UCSD.

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SP 2010_-_Chemical Mutagen - - in which one or more...

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