Heart_Pump_Figs_BW

Heart_Pump_Figs_BW - Cardiac Output / Regulation of Stroke...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
SA Node Electrical Conduction in the Heart 0 + - I V = IR R
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
ECG & Electrical Events in the Heart
Background image of page 2
Normal and Abnormal ECGs Normal Sinus Rhythm Atrial Fibrillation Ventricular Fibrillation P Q R S T No P waves Irregular R-R intervals Random, disorganized activity
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Mechanics of the Cardiac Cycle Late diastole Atrial systole Isovolumic ventricular contraction Ventricular ejection Isovolumic ventricular relaxation
Background image of page 4
Pressure - Volume Changes in Left Ventricle L Ventricular Volume (mL) 65 100 135 40 120 80 L Ventricular Pressure (mm Hg) B A C D EDV ESV Stroke Volume START
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Wiggers Diagram Correlates mechanical and electrical events during the cardiac cycle
Background image of page 6
Cardiac Output / Regulation of Heart Rate Cardiac Output (CO) = heart rate × stroke volume e.g., 72 beats/min × 70 mL/beat = ~ 5 L/min CO regulated by varying heart rate, stroke volume, or both. Regulation of Heart Rate ( Mainly via ANS): Normal HR = 60 / min 40 / min 100 / min 120 / min propranolol -blocker) atropine (mAChR blocker) both (max. parasymp. effect) (max. symp. effect) (intrinsic heart rate)
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Cardiac Output / Regulation of Stroke Volume Stroke volume force of contraction Force of contraction initial length of fibers, contractility 300 100 200 400 100 200 (135) (70) EDV (mL) [initial length of fibers] Stroke Volume (mL) [force of contraction] Normal resting values Starling Curve EDV depends on venous return, due to Skeletal muscle pump / Respiratory pump / Sympathetic vasoconstriction of veins Positive Inotropic Effect of Norepinephrine 300 100 200 400 100 200 EDV (mL) [initial length of fibers] Stroke Volume (mL) [force of contraction] Control Norepi Heart Failure Insufficient Cardiac Pumping Heart is unable to pump sufficient blood. Compensatory changes may result in increased blood volume and fluid congestion, enlargement of heart (cardiomegaly) Normal CHF Some Medications : Diuretics Vasodilators ACE Inhibitors -Blockers Angiotensin II Receptor Antagonists Digitalis...
View Full Document

This note was uploaded on 05/03/2010 for the course BISC 307L taught by Professor Herrera during the Spring '08 term at USC.

Page1 / 10

Heart_Pump_Figs_BW - Cardiac Output / Regulation of Stroke...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online