Volume_Osmol_Acid-Base_BW

Volume_Osmol_Acid-Base_BW - Phosphates, ammonia in urine...

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1. Ingest salt and water Excrete hypertonic urine 2. Ingest isotonic salt Excrete isotonic urine 3. Ingest water only Excrete dilute urine 4. Ingest salt only Thirst, Excretion of hypertonic urine 5. Replace sweat loss with water Risk of low plasma Na+ & K+ 1 2 3 4 5 6 7 8 6. Typical dehydration See next slide for response 7. Hemorrhage Stop, then replace with blood or isotonic NaCl 8. Incomplete compensation for #5
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Compensation for Severe Dehydration
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Acid – Base Balance 7.42 7.38 Plasma pH Acidosis ( CNS activity) Alkalosis ( CNS activity) H+ Input Fatty acids Amino acids CO 2 (+H 2 O) Lactic acid Ketoacids pH Buffers: HCO 3 - in ECF Protein (incl. Hb), phosphates in cells
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Unformatted text preview: Phosphates, ammonia in urine DIET METABOLISM H+ Output H+ CO 2 (+H 2 O) LUNGS KIDNEYS Summary of Renal Response to Acidosis hydrogen phosphate ion dihydrogen phosphate ion Prox. Tubule: H+ Secretion / HCO 3- Reabsorption Collecting Duct: Type A Cells in Acidosis Collecting Duct: Type B Cells in Alkalosis Acid Base Disturbances Respiratory Acidosis CO 2 + H 2 O H 2 CO 3 H+ + HCO 3-Metabolic Acidosis CO 2 + H 2 O H 2 CO 3 H + + HCO 3-Respiratory Alkalosis CO 2 + H 2 O H 2 CO 3 H+ + HCO 3-H+ HCO 3-...
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Volume_Osmol_Acid-Base_BW - Phosphates, ammonia in urine...

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