330JP13 - BISC 330L Dr. John Petruska 330JP13.ppt Lecture...

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BISC 330L Dr. John Petruska 330JP13.ppt Lecture 12 Appendix: Cell Membranes and Lecture 13 Protein Targeting to Membranes References: (3rd Ed 2005), Chap. 9.1, 31.3 (6th Ed 2007), Chap. 11.3, 30.6
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Fig. 2.11 Cytoskeleton is a network (gel) of protein filaments and micotubules that self-assemble by aggregation of protein subunits sythezised in cytoplasm. . QuickTime ò and a TIFF (Uncompressed) decompressor are needed to see this picture.
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Fig. 9.6 Fluid mosaic model of membrane structure. Lipids and and proteins move rapidly in the plane of membrane, but transverse motion across lipid bilayer is much slower and needs special enzymes ( flippases for phospholipids, translocons for proteins):. (lumen or extracellular space) (cytoplasm)
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Proteins are delivered to their proper cell compartment by translocation Prokaryotic proteins destined for translocation are synthesized as preproteins with amino-terminal leader sequences Eukaryotic proteins are routed through protein sorting and
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330JP13 - BISC 330L Dr. John Petruska 330JP13.ppt Lecture...

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