CHBE10 - Chemical Engineering and Pharmaceutical R&D...

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Chemical Engineering and Pharmaceutical R&D Christopher Burcham, Ph.D. Principal Research Scientist Chemical Product Research and Development
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CLB; April 20, 2009 2 Introduction Education BS Chemical Engineering, University of Illinois at Urbana-Champaign, Fall 1987 - Jan. 1992 PhD Chemical Engineering, Princeton University, Fall 1992 - Jan. 1998. Work Experience Undergraduate Research Assistant, 1989 – 1990 Undergraduate Teaching Assistant, 1990 – 1991 Internship – The Pillsbury Company, 1990 Internship – Mobil Oil Company, 1991 & 1992 Dow Chemical and Dow AgroSciences, 1998 – 2002 Eli Lilly and Company, 2002 – present – Manufacturing Science and Technology, 2002 – 2005 – Chemical Product Research and Development, 2005 – present
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CLB; April 20, 2009 3 Outline Introduction to Eli Lilly and Company Experiences that I have had How these experiences have shaped my career choices and career path A day in the life… What do I do on an average day Examples of Pharma R&D Projects Question and Answer Anytime - please feel free to interrupt
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CLB; April 20, 2009 4 Lilly at a Glance Headquartered in Indianapolis $20.4 Billion in sales (2008) Over 39,000 employees worldwide 7,500 in R&D (8 countries) 12,000 in Indiana 19,000 in US Clinical research in 50 countries and products marketed in 143 countries Manufacturing facilities in 13 countries Have launched eleven new products since 2001 Pipeline and portfolio focused on first-in-class or best-in-class products that meet unmet medical needs Elanco Animal Health ($1 Billion in sales (2008))
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CLB; April 20, 2009 5 A heritage more than 130 years strong May 10, 1876 Company founded by U.S. Civil War veteran and pharmaceutical chemist Colonel Eli Lilly Colonel Lilly’s priorities ± Manufacture high-quality products ± Recruit the best employees ± Satisfy the customer ± Develop new products Eli Lilly and Company: Modest Yet Strong Beginnings
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CLB; April 20, 2009 6 First research policy established in 1898 “To contribute to the progress of medicine by developing new and superior agents through research.” Eli Lilly and Company: Always a Commitment to Scientific Research
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CLB; April 20, 2009 7 Lilly Breakthrough Products ** Lilly has launched eleven products since 2001 ** Malignant pleural mesothelioma and lung cancer ** Type II diabetes (developed and marketed in partnership with Amylin pharmaceuticals) ** Erectile dysfunction ** Major depression and PNP (Partnership with Quintiles) Osteoporosis in women past menopause ** Osteoporosis for men and women in post menopause who are susceptible to fractures Cancer (pancreatic and non-small-cell lung cancer; bladder and breast cancer in Europe) Type 1 & Type 2 Diabetes Growth deficiency Type 1 & Type 2 Diabetes Cardiac ischemic complications (developed by Centocor, marketed by Lilly) ** Treatment of ADHD ** Treatment of Bipolar depression ** Treatment of severe sepsis ** Stress urinary incontinence (marketed in Europe with Boehringer Ingelheim) Schizophrenia, bipolar mania, and bipolar maintenance ** Colorectal cancer, head and neck cancer (2006) (Bristol-Myers Squibb Co. in NA and Japan and Merck KGaA) **
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CHBE10 - Chemical Engineering and Pharmaceutical R&D...

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