ch14,15.Pt3 - cells R T Glycogen synthase is...

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1 Regulation of glycogen metabolism: glycogen phosphorylase 15-34 Tense (T) Relaxed (R) Allosteric control of glycogen phosphorylase (PP1) Allosteric control of glycogen synthase 15-37 15-39 Insulin inactivates GSK3 via a phosphorylation cascade 15-35 A phosphorylation cascade also controls glycogen phosphorylase (only on phosphorylase b) Blood glucose level is regulated by liver glycogen metabolism
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2 15-36 Phosphorylase a is glucose sensor in liver
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Unformatted text preview: cells: R T Glycogen synthase is glucose-6-phosphate sensor in liver 15-37 15-40 Increased glycogen synthesis Activates PP1 dephosphorylates: •Phosphorylase kinase •Gycogen phosphorylase •Glycogen synthase Insulin Inhibits PP1 increased glycogen breakdown Regulation of PP1 by protein-protein interaction 15-41 Hormonal control of liver carbohydrate metabolism 15-42...
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ch14,15.Pt3 - cells R T Glycogen synthase is...

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